Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3345871 | 0.85 | CHRM2 (0.35) | CHRM2CHRM1GRM5DYRK1ASCN5A | |
| SCHEMBL3346516 | 0.85 | ALOX5 (0.37) | CHRM2CHRM1GRM5DYRK1ASCN5A | |
| SCHEMBL3347130 | 0.82 | CA12 (0.38) | CHRM2CHRM1DYRK1ASCN5A | |
| SCHEMBL3347334 | 0.81 | GRM5 (0.37) | CHRM2CHRM1PTGDR2GRM5 | |
| SCHEMBL3348468 | 0.80 | GRM5 (0.45) | GRM5DYRK1ASCN5A | |
| SCHEMBL3348895 | 0.79 | CHRM2 (0.40) | CHRM2CHRM1PTGDR2GRM5DYRK1A | |
| SCHEMBL3351121 | 0.77 | GRM5 (0.34) | GRM5DYRK1A | |
| SCHEMBL3348444 | 0.76 | CHRM2 (0.35) | CHRM2CHRM1GRM5DYRK1ASCN5A | |
| SCHEMBL3346158 | 0.76 | CYP2A6 (0.44) | GRM5 | |
| SCHEMBL3346833 | 0.75 | GRM5 (0.50) | PTGDR2GRM5DYRK1ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | claimed |
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |