Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | HEXA | P06865 | 1/20 | 0.31 |
| ▸ | HEXB | P07686 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL750293 | 0.83 | ALOX5 (0.38) | HEXAHEXBTDP1ALDH1A1 | |
| SCHEMBL1370479 | 0.82 | ALDH1A1 (0.36) | MCL1ALDH1A1 | |
| SCHEMBL15819864 | 0.81 | HEXA (0.39) | HEXAHEXBACHENPC1RAB9A | |
| SCHEMBL8913087 | 0.80 | ABL1 (0.43) | NPC1RAB9A | |
| SCHEMBL6397215 | 0.80 | KIF11 (0.40) | NPC1RAB9AALDH1A1 | |
| SCHEMBL8763861 | 0.78 | RAPGEF4 (0.33) | — | |
| SCHEMBL510261 | 0.78 | RAB9A (0.36) | MCL1HEXAHEXBACHETDP1 | |
| SCHEMBL215511 | 0.77 | — | — | |
| SCHEMBL7818370 | 0.76 | MCL1 (0.39) | MCL1ARACHETDP1NPC1 | |
| SCHEMBL2154634 | 0.75 | MCL1 (0.41) | MCL1ARACHETDP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042657-A1 | USE OF DIINDOLYLMETHANE (DIM) COMPOUNDS AND DERIVATIVES AS NEUROPROTECTIVE AGENTS | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2010-04-15 | — | — | WO | claimed |
| US-20100087504-A1 | Use of Diindolylmethane (DIM) Compounds and Derivatives as Neuroprotective Agents | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2010-04-08 | — | — | US | claimed |
| US-8580843-B2 | Use of diindolylmethane (DIM) compounds and derivatives as neuroprotective agents | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2013-11-12 | — | — | US | disclosed |
| WO-2010042657-A1 | USE OF DIINDOLYLMETHANE (DIM) COMPOUNDS AND DERIVATIVES AS NEUROPROTECTIVE AGENTS | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2010-04-15 | — | — | WO | disclosed |
| US-20100087504-A1 | Use of Diindolylmethane (DIM) Compounds and Derivatives as Neuroprotective Agents | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2010-04-08 | — | — | US | disclosed |
| US-5003081-A | Useful in preparation of azo dyes | BASF AKTIENGESELLSCHAFT (DE) | 1991-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087504-A1 | Use of Diindolylmethane (DIM) Compounds and Derivatives as Neuroprotective Agents | AIFM1, NLN, SNCA | MCL1 1833/4885HEXA 2504/4885HEXB 3389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.