Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 10/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 9/20 | 0.39 |
| ▸ | GRM5 | P41594 | 8/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346499 | 0.90 | CDK2 (0.35) | CDK2CCNE1 | |
| SCHEMBL3346921 | 0.86 | KCNN3 (0.37) | CDK2CCNE1GRM5 | |
| SCHEMBL3345910 | 0.86 | GRM5 (0.35) | CDK2CCNE1GRM5 | |
| SCHEMBL3351713 | 0.86 | KCNN3 (0.38) | CDK2CCNE1GRM5 | |
| SCHEMBL3351298 | 0.83 | GRM5 (0.33) | GRM5CYP2A6 | |
| SCHEMBL3346746 | 0.83 | KCNN1 (0.38) | CDK2CCNE1GRM5 | |
| SCHEMBL3351751 | 0.82 | CDK2 (0.38) | CDK2CCNE1GRM5 | |
| SCHEMBL3347648 | 0.82 | GRM5 (0.33) | CDK2CCNE1GRM5 | |
| SCHEMBL3345946 | 0.81 | GRM5 (0.39) | CDK2CCNE1GRM5CYP2C9CYP2C19 | |
| SCHEMBL3346510 | 0.81 | GRM5 (0.37) | GRM5CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | claimed |
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |