SCHEMBL33492

SCHEMBL33492

C=CC(=O)NCCCN=C=O

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.50
ZDHHC2 Q9UIJ5 1/20 0.50
ALDH1A1 P00352 1/20 0.43
TSHR P16473 1/20 0.43
MAPK1 P28482 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
MAPT P10636 1/20 0.38
KEAP1 Q14145 3/20 0.38
NFE2L2 Q16236 3/20 0.38
TGM2 P21980 4/20 0.37
GAA P10253 1/20 0.37
KMT2A Q03164 1/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33728 0.89 TSHR (0.46) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL2364074 0.79 ZDHHC20 (0.55) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL1561467 0.77 ZDHHC20 (0.68) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL632264 0.77 ZDHHC20 (0.75) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL18116076 0.76 KEAP1 (0.42) MAPK1MAPTKEAP1NFE2L2
SCHEMBL270209 0.75 ZDHHC20 (0.79) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL1591868 0.75 ZDHHC20 (0.79) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL8405507 0.75 ZDHHC20 (0.79) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL1592093 0.75 ZDHHC20 (0.79) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL269468 0.75 ZDHHC20 (0.79) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240327661-A1 POLYMER, COPOLYMER, INK, INK CONTAINER, IMAGE FORMING METHOD, IMAGE FORMING DEVICE, AND BACKSHEET FOR SOLAR CELL RICOH COMPANY, LTD. (JP) 2024-10-03 US disclosed
EP-2470616-B1 ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH ACYLAZIRIDINE CROSSLINKING AGENTS 3M INNOVATIVE PROPERTIES CO (US) 2013-05-29 EP disclosed
US-20130053508-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH ACYLAZIRIDINE CROSSLINKING AGENTS 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-02-28 US disclosed
US-8349962-B2 Acrylic pressure-sensitive adhesives with acylaziridine crosslinking agents 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-01-08 US disclosed
EP-2470616-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH ACYLAZIRIDINE CROSSLINKING AGENTS 3M Innovative Properties Company (US) 2012-07-04 EP disclosed
US-20120028043-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH ACYLAZIRIDINE CROSSLINKING AGENTS 3M INNOVATIVE PROPERTIES COMPANY 2012-02-02 US disclosed
US-8067504-B2 Acrylic pressure-sensitive adhesives with acylaziridine crosslinking agents 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-11-29 US disclosed
US-20110054115-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH ACYLAZIRIDINE CROSSLINKING AGENTS 3M INNOVATIVE PROPERTIES COMPANY 2011-03-03 US disclosed
WO-2011025651-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH ACYLAZIRIDINE CROSSLINKING AGENTS 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-03-03 WO disclosed
EP-0146326-B1 SULFOPOLYESTER-CONTAINING PHOTOPOLYMER SYSTEMS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-03-13 EP disclosed
US-4956265-A POLYUNSATURATED WITH ESTER AND CARBOXY GROUPS; PROTECTIVE COATINGS, GRAPHIC ARTS, PHOTORESTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-09-11 US disclosed
US-4914165-A PHOTOCROSSLINKABLE POLYEPOXIDE POLYESTERS USING POLY (ETHYLENICALLY-UNSATURATED)ALKANOLS AND DICARBOXYLIC ACIDS; PROTECTIVE COATINGS; GRAPHIC ARTS; WEAR RESISTANCE; ADHESION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-04-03 US disclosed
EP-0329298-A2 Radiation crosslinkable compositions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-08-23 EP disclosed
US-4855384-A POLYURETHANES FROM POLYESTERS OR POLY OF SULFOAROMATIC DICARBOCYLIC ACIDS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-08-08 US disclosed
US-4746717-A COATINGS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-05-24 US disclosed
US-4558149-A FILMS;COATINGS;PHOTORESISTS;LOW MOLECULAR WEIGHT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-12-10 US disclosed
EP-0146326-A2 Sulfopolyester-containing photopolymer systems MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-06-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110054115-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH ACYLAZIRIDINE CROSSLINKING AGENTS AAAS, PTK2, MDN1 ZDHHC20 2838/4885ZDHHC2 2345/4885ALDH1A1 492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.