SCHEMBL2364074

SCHEMBL2364074

C=CC(=O)NCCCN=O

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.55
ZDHHC2 Q9UIJ5 1/20 0.55
TSHR P16473 2/20 0.48
ALDH1A1 P00352 1/20 0.48
MAPK1 P28482 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
MAPT P10636 1/20 0.42
TGM2 P21980 8/20 0.40
GAA P10253 1/20 0.40
KMT2A Q03164 2/20 0.35
ATM Q13315 1/20 0.35
KDM4E B2RXH2 1/20 0.31
DDAH1 O94760 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1561467 0.82 ZDHHC20 (0.68) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL632264 0.82 ZDHHC20 (0.75) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL1592093 0.80 ZDHHC20 (0.79) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL8405507 0.80 ZDHHC20 (0.79) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL1401845 0.80 ZDHHC20 (0.79) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL1591868 0.80 ZDHHC20 (0.79) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL270209 0.80 ZDHHC20 (0.79) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL58169 0.80 ZDHHC20 (0.79) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL269468 0.80 ZDHHC20 (0.79) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL16619465 0.79 ZDHHC20 (0.50) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10647659-B2 Process for productions of formamides and acrylamides SHENZHEN YOUWEI TECHNOLOGY HOLDINGS GROUP CO., LTD. (CN) 2020-05-12 US disclosed
US-20200048186-A1 Process for Productions of Formamides and Acrylamides SHENZHEN YOUWEI TECHNOLOGY HOLDINGS GROUP CO.,LTD. (CN) 2020-02-13 US disclosed
EP-3181619-A1 POLYMER FUNCTIONAL FILM, PRODUCTION METHOD THEREOF, AND STACK OR DEVICE PROVIDED WITH POLYMER FUNCTIONAL FILM Fujifilm Corporation (JP) 2017-06-21 EP disclosed
US-9625392-B2 Detecting organic contaminants THONHAUSER GMBH (AT) 2017-04-18 US disclosed
US-20160061739-A1 DETECTING ORGANIC CONTAMINANTS THONHAUSER GMBH (AT) 2016-03-03 US disclosed
US-7989411-B2 Composition which contains a mixture of mono-, di and triglycerides and glycerine KAO CORPORATION, S.A. (ES) 2011-08-02 US disclosed
US-RE41585-E1 Method for controlling the rheology of an aqueous fluid and gelling agent therefor AKZO NOBEL NV 2010-08-24 US disclosed
US-20100035781-A1 Composition which Contains a Mixture of Mono-, Di and Triglycerides and Glycerine KAO CORPORATION, S.A. (ES) 2010-02-11 US disclosed
EP-2029711-B1 COMPOSITION WHICH CONTAINS A MIXTURE OF MONO-, DI-, AND TRIGLYCERIDES AND GLYCERINE KAO CORP SA (ES) 2010-02-10 EP disclosed
EP-1292651-B1 VISCOELASTIC SURFACTANTS AND COMPOSITIONS CONTAINING SAME AKZO NOBEL NV (NL) 2010-01-06 EP disclosed
EP-1292651-A2 VISCOELASTIC SURFACTANTS AND COMPOSITIONS CONTAINING SAME Akzo Nobel N.V. (NL) 2003-03-19 EP disclosed
US-6506710-B1 Gelling agent composition which comprises at least one glycol as a solvent, and at least one amidoamine oxide gelling agent AKZO NOBEL N.V. (NL) 2003-01-14 US disclosed
EP-1042425-B1 A METHOD FOR CONTROLLING THE RHEOLOGY OF AN AQUEOUS FLUID AND GELLING AGENT THEREFOR AKZO NOBEL NV (NL) 2002-11-06 EP disclosed
US-20020147114-A1 Acid thickeners and uses thereof NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2002-10-10 US disclosed
WO-2001081499-A2 VISCOELASTIC SURFACTANTS AND COMPOSITIONS CONTAINING SAME AKZO NOBEL N.V. (NL) 2001-11-01 WO disclosed
US-6265373-B1 WEIGHT RATIO OF TRIGLYCERIDE/DIGLYCERIDE/MONOGLYCERIDE BEING 46 TO 90/9 TO 35/1 TO 15. KAO CORPORATION S.A. (ES) 2001-07-24 US disclosed
US-6239183-B1 INJECTING VISCOELASTIC FLUID CONTAINING AMIDOAMINE OXIDE GELLING AGENT AND QUATERNARY AMMONIUM SALT OF AROMATIC DICARBOXYLIC ACID INTO SUBTERRANEAN FORMATION AKZO NOBEL NV (NL) 2001-05-29 US disclosed
EP-1045021-A1 Composition comprising a mixture of alkoxylated mono-, di- and triglycerides and glycerine KAO CORPORATION, S.A. (ES) 2000-10-18 EP disclosed
EP-1042425-A1 A METHOD FOR CONTROLLING THE RHEOLOGY OF AN AQUEOUS FLUID AND GELLING AGENT THEREFOR Akzo Nobel N.V. (NL) 2000-10-11 EP disclosed
WO-1999032572-A1 A METHOD FOR CONTROLLING THE RHEOLOGY OF AN AQUEOUS FLUID AND GELLING AGENT THEREFOR AKZO NOBEL N.V. (NL) 1999-07-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10647659-B2 Process for productions of formamides and acrylamides PFAS, FASN, AGPS ZDHHC20 366/4885ZDHHC2 201/4885TSHR 4795/4885
US-20100035781-A1 Composition which Contains a Mixture of Mono-, Di and Triglycerides and Glycerine MGLL, ABHD6, LIPC ZDHHC20 98/4885ZDHHC2 108/4885TSHR 2522/4885
US-20200048186-A1 Process for Productions of Formamides and Acrylamides PFAS, FASN, AGPS ZDHHC20 366/4885ZDHHC2 201/4885TSHR 4795/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.