Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4607483 | 0.98 | ALDH1A1 (0.44) | ALDH1A1SMARCA2PBRM1SMN1; SMN2POLB | |
| SCHEMBL761104 | 0.95 | — | — | |
| SCHEMBL20458913 | 0.82 | CHRNB2 (0.45) | — | |
| SCHEMBL20458953 | 0.82 | ADRA1A (0.36) | ALDH1A1SMARCA2PBRM1SMN1; SMN2MAPT | |
| SCHEMBL15473924 | 0.82 | NCF1 (0.44) | ADRA1AADRA1BKDM4ECHRM2CHRM4 | |
| SCHEMBL5029237 | 0.80 | ADRB1 (0.47) | ALDH1A1KDM4E | |
| SCHEMBL21047591 | 0.79 | PRKDC (0.40) | ALDH1A1SMN1; SMN2POLBMAPTADRA1A | |
| SCHEMBL11459166 | 0.79 | NPC1 (0.41) | ALDH1A1SMN1; SMN2POLBMAPTALOX15 | |
| SCHEMBL15471361 | 0.78 | ADRA1A (0.36) | ALDH1A1SMN1; SMN2MAPTADRA1AADRA1B | |
| SCHEMBL31373496 | 0.77 | ADRA1A (0.35) | ALDH1A1SMN1; SMN2ALOX15ADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116918832-A | Composite biocontrol microbial agent, preparation method, application and application method | 甘肃省科学院生物研究所 | 2023-10-24 | — | — | CN | disclosed |
| CN-116762826-A | Plant pathogenic soil biological control agent, preparation method, application and application method | 甘肃省科学院生物研究所 | 2023-09-19 | — | — | CN | disclosed |
| CN-116024119-A | Streptomyces nigromaculatus and application thereof in prevention and control of root rot of solanaceous vegetables | 甘肃省科学院生物研究所 | 2023-04-28 | — | — | CN | disclosed |
| CN-110612297-A | Estrogen receptor proteolytic modulators and related methods of use | 阿尔维纳斯运营股份有限公司 | 2019-12-24 | — | — | CN | disclosed |
| WO-2010059922-A1 | PYRROLIDINE CARBOXAMIDE COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2010-05-27 | — | — | WO | disclosed |
| EP-1673078-A4 | BENZYLETHER AND BENZYLAMINO BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | MERCK & CO INC (US) | 2007-04-18 | — | — | EP | disclosed |
| EP-1673078-A2 | BENZYLETHER AND BENZYLAMINO BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | Merck & Co., Inc. (US) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005032471-A2 | BENZYLETHER AND BENZYLAMINO BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | MERCK & CO., INC. (US) | 2005-04-14 | — | — | WO | disclosed |