Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 3/20 | 0.34 |
| ▸ | NOS1 | P29475 | 3/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | HTR1F | P30939 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2265014 | 0.88 | DGAT1 (0.48) | ASH1LDGAT1KDM4CGRM2HCAR1 | |
| SCHEMBL20784146 | 0.84 | DGAT1 (0.38) | ASH1LDGAT1HTR1DDRD2SLC6A4 | |
| SCHEMBL12459068 | 0.81 | KDM4C (0.39) | KDM4CHTR1DDRD2SLC6A4NOS3 | |
| SCHEMBL6743242 | 0.81 | HTR7 (0.40) | DGAT1KDM4CGRM2HCAR1HTR1D | |
| SCHEMBL3352865 | 0.80 | HTR1D (0.51) | HTR1DDRD2SLC6A4NOS3NOS1 | |
| SCHEMBL3354541 | 0.78 | OPRM1 (0.36) | HTR1DDRD2SLC6A4NOS3NOS1 | |
| SCHEMBL3358911 | 0.78 | OPRM1 (0.36) | HTR1DDRD2SLC6A4NOS3NOS1 | |
| SCHEMBL3355563 | 0.78 | OPRM1 (0.47) | HTR1DDRD2SLC6A4NOS3NOS1 | |
| SCHEMBL3354536 | 0.78 | OPRM1 (0.36) | HTR1DDRD2SLC6A4NOS3NOS1 | |
| SCHEMBL29776579 | 0.78 | DGAT1 (0.43) | DGAT1KDM4CGRM2HCAR1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |