SCHEMBL33526792

SCHEMBL33526792

O=C1OCCc2c(Br)ccc(F)c21

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ABCC9 O60706 9/20 0.42
KCNJ11 Q14654 9/20 0.42
ABCC8 Q09428 7/20 0.42
KCNJ8 Q15842 7/20 0.42
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
KDM4E B2RXH2 1/20 0.36
EED O75530 3/20 0.33
SUZ12 Q15022 3/20 0.33
EZH2 Q15910 3/20 0.33
HSD11B1 P28845 2/20 0.32
ALDH1A1 P00352 1/20 0.32
PARP1 P09874 1/20 0.31
PARP10 Q53GL7 1/20 0.30
PARP11 Q9NR21 1/20 0.30
IL1RN P18510 1/20 0.30
ERAP2 Q6P179 1/20 0.30
ERAP1 Q9NZ08 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL855174 0.82 ABCC9 (0.39) ABCC9KCNJ11ABCC8KCNJ8
SCHEMBL33526483 0.76 MAOA (0.38) ABCC9KCNJ11ABCC8KCNJ8MAOA
SCHEMBL12261417 0.74 KDM4E (0.56) ABCC9KCNJ11ABCC8KCNJ8KDM4E
SCHEMBL14720202 0.72 ABCC9 (0.36) ABCC9KCNJ11ABCC8KCNJ8MAOA
SCHEMBL12565316 0.72 LMNA (0.42) ABCC9KCNJ11ABCC8KCNJ8MAOA
SCHEMBL18797086 0.71 ABCC9 (0.33) ABCC9KCNJ11ABCC8KCNJ8PARP1
SCHEMBL854104 0.70 ALOX5 (0.38) ABCC9KCNJ11ABCC8KCNJ8MAOA
SCHEMBL17128311 0.69 PARP10 (0.51) ABCC9KCNJ11ABCC8KCNJ8MAOA
SCHEMBL21752292 0.69 LMNA (0.39) ABCC9KCNJ11ABCC8KCNJ8MAOA
SCHEMBL33526277 0.67 MAOA (0.36) MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS LILLY CO ELI (US) 2026-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS GIPR, GLP1R, GPR119 ABCC9 1207/4885KCNJ11 901/4885ABCC8 968/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.