Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 16/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 16/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 12/20 | 0.39 |
| ▸ | KCNJ8 | Q15842 | 12/20 | 0.39 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | NEK2 | P51955 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | NEK6 | Q9HC98 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL854104 | 0.84 | ALOX5 (0.38) | ABCC9KCNJ11ABCC8KCNJ8NUAK1 | |
| SCHEMBL855093 | 0.84 | PIM1 (0.37) | NUAK1IGF1RMETPIM1SRC | |
| SCHEMBL33526792 | 0.82 | ABCC9 (0.42) | ABCC9KCNJ11ABCC8KCNJ8 | |
| SCHEMBL12553463 | 0.78 | MAOA (0.47) | NUAK1IGF1RMETPIM1SRC | |
| SCHEMBL855135 | 0.78 | ALDH1A1 (0.40) | NUAK1IGF1RMETPIM1SRC | |
| SCHEMBL12553377 | 0.78 | AKT1 (0.41) | NUAK1IGF1RMETPIM1SRC | |
| SCHEMBL12553458 | 0.74 | KDM4E (0.57) | NUAK1IGF1RMETPIM1SRC | |
| SCHEMBL286736 | 0.74 | NUAK1 (0.45) | ABCC9KCNJ11ABCC8KCNJ8NUAK1 | |
| SCHEMBL16555552 | 0.71 | EPAS1 (0.34) | NUAK1IGF1RMETPIM1SRC | |
| SCHEMBL855948 | 0.70 | KCNJ1 (0.44) | ABCC9KCNJ11ABCC8KCNJ8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8604221-B2 | Production method of halogen-substituted phthalide | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-12-10 | — | — | US | disclosed |
| US-20120142946-A1 | PRODUCTION METHOD OF HALOGEN-SUBSTITUTED PHTHALIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-06-07 | — | — | US | disclosed |
| EP-2433933-A1 | PRODUCTION METHOD OF HALOGEN-SUBSTITUTED PHTHALIDE | Sumitomo Chemical Company, Limited (JP) | 2012-03-28 | — | — | EP | disclosed |