Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL33527372

COc1nc(-c2cc(C(F)(F)F)nn2CC(C)(C)N)ns1.O=C(O)C(F)(F)F

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 3/20 0.37
PTGER1 P34995 1/20 0.35
TP53 P04637 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HDAC3 O15379 2/20 0.32
HDAC4 P56524 2/20 0.32
HDAC1 Q13547 2/20 0.32
HDAC7 Q8WUI4 2/20 0.32
HDAC2 Q92769 2/20 0.32
HDAC10 Q969S8 2/20 0.32
HDAC11 Q96DB2 2/20 0.32
HDAC8 Q9BY41 2/20 0.32
HDAC6 Q9UBN7 2/20 0.32
HDAC9 Q9UKV0 2/20 0.32
HDAC5 Q9UQL6 2/20 0.32
NCOR2 Q9Y618 2/20 0.32
SLC16A3 O15427 1/20 0.32
SLC16A1 P53985 1/20 0.32
ALDH1A1 P00352 2/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33526439 0.81 PTGS2 (0.34) PTGS2PTGER1TP53L3MBTL1HDAC3
Hydrochloric Acid SCHEMBL33527204 0.78 HDAC3 (0.32) HDAC3HDAC4HDAC1HDAC7HDAC2
Trifluoroacetic Acid SCHEMBL33525935 0.78 LOXL2 (0.31)
Trifluoroacetic Acid SCHEMBL31752113 0.72 IDO1 (0.35) TP53L3MBTL1HDAC3HDAC4HDAC1
Hydrochloric Acid SCHEMBL34466698 0.67 TP53 (0.42) TP53L3MBTL1ALDH1A1LMNAHPGD
Hydrochloric Acid SCHEMBL33526345 0.67 L3MBTL1 (0.40) PTGS2TP53L3MBTL1ALDH1A1KDM4E
Hydrochloric Acid SCHEMBL33526537 0.66 PTGS2 (0.36) PTGS2TP53LMNAMAPT
Hydrochloric Acid SCHEMBL33527174 0.64 RAB9A (0.33) PTGS2HDAC3HDAC4HDAC1HDAC7
Hydrochloric Acid SCHEMBL33527022 0.63 TP53 (0.34) TP53L3MBTL1HDAC3HDAC4HDAC1
Hydrochloric Acid SCHEMBL33526538 0.63 LMNA (0.46) TP53L3MBTL1ALDH1A1LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS LILLY CO ELI (US) 2026-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS GIPR, GLP1R, GPR119 PTGS2 2150/4885PTGER1 688/4885TP53 4863/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.