Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | CTSA | P10619 | 4/20 | 0.38 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3347753 | 0.90 | DHODH (0.41) | DHODHPIM1PIM2FFAR1FFAR4 | |
| SCHEMBL3431483 | 0.89 | FFAR1 (0.43) | DHODHPIM1PIM2FFAR1FFAR4 | |
| SCHEMBL3430749 | 0.89 | GAA (0.43) | DHODHFFAR1FFAR4GRIN2DGRIN3B | |
| SCHEMBL3346362 | 0.84 | DHODH (0.39) | DHODHPIM1PIM2XDHGRIN1 | |
| SCHEMBL3350657 | 0.83 | DHODH (0.41) | DHODHPTGDR2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3347691 | 0.82 | FFAR4 (0.40) | DHODHFFAR1FFAR4GRIN1GRIN2B | |
| SCHEMBL3430044 | 0.80 | FFAR1 (0.48) | DHODHPIM1PIM2FFAR1FFAR4 | |
| SCHEMBL3346002 | 0.80 | GRIN2D (0.41) | DHODHFFAR1FFAR4GRIN2DGRIN3B | |
| SCHEMBL3346086 | 0.77 | PTGER4 (0.44) | DHODHGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4727593 | 0.77 | KDM4E (0.41) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010053757-A1 | 2 -OXOQUINOXALIN BLOCKERS OF THE LATE SODIUM CHANNEL | GILEAD PALO ALTO, INC. (US) | 2010-05-14 | — | — | WO | disclosed |