Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | VNN1 | O95497 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3430136 | 0.88 | DHODH (0.39) | DHODHPIM1KDM4EHSD17B10PIM2 | |
| SCHEMBL3431483 | 0.84 | FFAR1 (0.43) | DHODHPIM1PIM2XDHSUCNR1 | |
| SCHEMBL3353013 | 0.84 | DHODH (0.45) | DHODHPIM1PIM2XDHGRIN1 | |
| SCHEMBL3347753 | 0.81 | DHODH (0.41) | DHODHPIM1PIM2XDHTRPA1 | |
| SCHEMBL3430772 | 0.78 | KDM4E (0.38) | KDM4EHSD17B10ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL3347691 | 0.77 | FFAR4 (0.40) | DHODHGRIN1GRIN2B | |
| SCHEMBL3432976 | 0.75 | GSK3B (0.39) | KDM4EHSD17B10ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL3430044 | 0.75 | FFAR1 (0.48) | DHODHPIM1PIM2XDH | |
| SCHEMBL3430749 | 0.73 | GAA (0.43) | DHODHKDM4EHSD17B10GRIN1GRIN2B | |
| SCHEMBL3346086 | 0.72 | PTGER4 (0.44) | DHODHKDM4EGRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010053757-A1 | 2 -OXOQUINOXALIN BLOCKERS OF THE LATE SODIUM CHANNEL | GILEAD PALO ALTO, INC. (US) | 2010-05-14 | — | — | WO | claimed |