Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.41 |
| ▸ | PIM1 | P11309 | 3/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3353013 | 0.90 | DHODH (0.45) | DHODHPIM1PIM2XDHCYP1A2 | |
| SCHEMBL3431483 | 0.83 | FFAR1 (0.43) | DHODHPIM1PIM2XDHTRPC5 | |
| SCHEMBL3346362 | 0.81 | DHODH (0.39) | DHODHPIM1PIM2XDHTRPA1 | |
| SCHEMBL3430749 | 0.79 | GAA (0.43) | DHODHCYP1A2CYP2C19GRIN1GRIN2B | |
| SCHEMBL3347691 | 0.76 | FFAR4 (0.40) | DHODHGRIN1GRIN2BFFAR1FFAR4 | |
| SCHEMBL3430044 | 0.74 | FFAR1 (0.48) | DHODHPIM1PIM2XDHMGLL | |
| SCHEMBL3350657 | 0.73 | DHODH (0.41) | DHODHCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3346086 | 0.71 | PTGER4 (0.44) | DHODHCYP2C9GRIN1GRIN2B | |
| SCHEMBL3349649 | 0.70 | FFAR1 (0.45) | DHODHPIM1PIM2XDHMGLL | |
| SCHEMBL3430136 | 0.69 | DHODH (0.39) | DHODHPIM1PIM2XDHTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010053757-A1 | 2 -OXOQUINOXALIN BLOCKERS OF THE LATE SODIUM CHANNEL | GILEAD PALO ALTO, INC. (US) | 2010-05-14 | — | — | WO | claimed |