Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | ICMT | O60725 | 2/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3351825 | 0.91 | ACHE (0.44) | ICMTMTNR1BSSTR5 | |
| SCHEMBL3354038 | 0.89 | NR1H2 (0.46) | ICMT | |
| SCHEMBL3352252 | 0.89 | CACNB4 (0.43) | ICMTMTNR1BKDM4E | |
| SCHEMBL13537524 | 0.83 | HRH3 (0.41) | HRH3ICMTMTNR1BKDM4ECNR2 | |
| SCHEMBL3358110 | 0.83 | HRH3 (0.55) | HRH3ICMTKDM4EMAPTCYP2A13 | |
| SCHEMBL3353183 | 0.81 | CTSB (0.53) | HRH3MTNR1BMAPTCNR2CNR1 | |
| SCHEMBL3351981 | 0.77 | ICMT (0.55) | HRH3ICMTKDM4EMAPTCNR2 | |
| SCHEMBL3349651 | 0.77 | HTR6 (0.41) | ICMTCNR2CNR1 | |
| SCHEMBL3357970 | 0.76 | NR1H2 (0.47) | ICMTKDM4E | |
| SCHEMBL3357664 | 0.75 | HRH3 (0.47) | HRH3ICMTKDM4EMAPTCYP2A13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |