Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | HTT | P42858 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | PRKACG | P22612 | 1/20 | 0.35 |
| ▸ | PRKACB | P22694 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3354155 | 0.81 | CDK2 (0.47) | KMT2AMAPTHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL3356042 | 0.81 | CACNB4 (0.52) | KMT2AHTTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL3352886 | 0.81 | MAPT (0.42) | F2RL3KMT2AASH1LMAPTHTT | |
| SCHEMBL3351079 | 0.80 | HTR6 (0.48) | MAPTHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL3354509 | 0.80 | CACNB4 (0.54) | KMT2AHTTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL3353183 | 0.79 | CTSB (0.53) | KMT2AMAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL3349651 | 0.79 | HTR6 (0.41) | ASH1LPRKACAPRKACGPRKACBREN | |
| SCHEMBL3352477 | 0.79 | ALDH1A1 (0.52) | F2RL3KMT2AASH1LMAPTHTT | |
| SCHEMBL3354060 | 0.78 | CNR2 (0.47) | KMT2AMAPTALDH1A1 | |
| SCHEMBL3354062 | 0.76 | KMT2A (0.41) | F2RL3KMT2AASH1LMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |