Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.41 |
| ▸ | ICMT | O60725 | 2/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | PRKACG | P22612 | 1/20 | 0.35 |
| ▸ | PRKACB | P22694 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | ASH1L | Q9NR48 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3352610 | 0.79 | F2RL3 (0.39) | PRKACAPRKACGPRKACBRENASH1L | |
| SCHEMBL3353333 | 0.79 | HTR6 (0.46) | HTR6HTR2ASLC6A4 | |
| SCHEMBL3351825 | 0.79 | ACHE (0.44) | ICMTHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL3351946 | 0.78 | DYRK1A (0.38) | DYRK1ARENNFATC1GSK3BASH1L | |
| SCHEMBL3352252 | 0.78 | CACNB4 (0.43) | ICMTHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL3354038 | 0.78 | NR1H2 (0.46) | HTR6ICMT | |
| SCHEMBL3353615 | 0.77 | HRH3 (0.41) | ICMTCNR1CNR2 | |
| SCHEMBL3353042 | 0.70 | HTR6 (0.47) | HTR6ICMTHTR2ASLC6A4 | |
| SCHEMBL31735441 | 0.70 | DYRK1A (0.43) | DYRK1ANFATC1GSK3BNPSR1CNR1 | |
| Hydrochloric Acid SCHEMBL19896294 | 0.69 | ALDH1A1 (0.44) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |