Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.41 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.41 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR1F | P30939 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30778513 | 0.93 | MAPT (0.46) | ALDH1A1MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL3357246 | 0.91 | MAPT (0.51) | ALDH1A1MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL29741245 | 0.87 | GLS (0.44) | ALDH1A1MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL3388874 | 0.87 | GLS (0.44) | ALDH1A1MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL3356604 | 0.85 | HTR1A (0.52) | MAPTSMN1; SMN2NPC1HTR1AHTR1B | |
| SCHEMBL3352833 | 0.82 | MAPT (0.45) | ALDH1A1MAPTSMN1; SMN2NPC1POLB | |
| SCHEMBL1868072 | 0.82 | L3MBTL1 (0.43) | SMN1; SMN2NPC1CYP1A2CYP2D6CDYL2 | |
| SCHEMBL1868073 | 0.82 | L3MBTL1 (0.43) | SMN1; SMN2NPC1CYP1A2CYP2D6CDYL2 | |
| SCHEMBL3357810 | 0.82 | ALDH1A1 (0.40) | ALDH1A1MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL3357749 | 0.81 | ALDH1A1 (0.43) | ALDH1A1MAPTCYP1A2SIRT2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |