Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | HTR1B | P28222 | 1/20 | 0.52 |
| ▸ | HTR1F | P30939 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | SCD | O00767 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29377201 | 0.90 | GLS (0.50) | HTR1AHTR1BHTR1FHTR7SCD | |
| SCHEMBL3355202 | 0.90 | GLS (0.50) | HTR1AHTR1BHTR1FHTR7SCD | |
| SCHEMBL3388874 | 0.90 | GLS (0.44) | HTR1AHTR1BHTR1FGLSALOX15 | |
| SCHEMBL29741245 | 0.90 | GLS (0.44) | HTR1AHTR1BHTR1FGLSALOX15 | |
| SCHEMBL3349251 | 0.87 | LMNA (0.44) | HTR1AHTR1BHTR1FHTR7SCD | |
| SCHEMBL30778513 | 0.87 | MAPT (0.46) | HTR1AHTR1BHTR1FGLSALOX15 | |
| SCHEMBL3357810 | 0.87 | ALDH1A1 (0.40) | HTR1AHTR1BHTR1FSCDGLS | |
| SCHEMBL3352833 | 0.87 | MAPT (0.45) | HTR1AHTR1BHTR1FHTR7ACHE | |
| SCHEMBL3353374 | 0.85 | ALDH1A1 (0.48) | HTR1AHTR1BHTR1FGLSMAPT | |
| SCHEMBL1868072 | 0.84 | L3MBTL1 (0.43) | HTR1AHTR1BHTR1FGLSNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |
| CN-1510034-A | Indazole compound, preparing method thereof and medicine composition containing the same | ɪά��ʵ���� | 2004-07-07 | — | — | CN | disclosed |
| EP-0902027-B1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR (FR) | 2001-07-25 | — | — | EP | disclosed |
| US-6046205-A | FOR TREATMENT OF VENOUS INSUFFICIENCY AND OF ASSOCIATED DISORDERS, AND ALSO IN THE TREATMENT OF MIGRAINE | ADIR ET COMPAGNIE (FR) | 2000-04-04 | — | — | US | disclosed |
| US-6020336-A | Indole and indazole compounds | LES LABORATOIRES SERVIER (FR) | 2000-02-01 | — | — | US | disclosed |
| EP-0902027-A1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-03-17 | — | — | EP | disclosed |