Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.42 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.42 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12253684 | 0.85 | HTR7 (0.55) | NPC1ALDH1A1POLBMAPTRAB9A | |
| SCHEMBL3353280 | 0.85 | HTR7 (0.53) | MAPTHTR7CDC7NOS3NOS1 | |
| SCHEMBL7805698 | 0.83 | HTR7 (0.45) | NPC1ALDH1A1POLBMAPTRAB9A | |
| SCHEMBL3357415 | 0.81 | HTR7 (0.42) | NPC1ALDH1A1POLBMAPTRAB9A | |
| SCHEMBL3358021 | 0.81 | HTR7 (0.47) | ALDH1A1POLBMAPTSMN1; SMN2HTR7 | |
| SCHEMBL3353526 | 0.81 | CDC7 (0.43) | NPC1ALDH1A1POLBMAPTRAB9A | |
| SCHEMBL3359093 | 0.81 | ALDH1A1 (0.41) | ALDH1A1POLBMAPTSMN1; SMN2HTR7 | |
| SCHEMBL3353782 | 0.81 | ALDH1A1 (0.42) | ALDH1A1HTR7SIRT2CYP1A2CDC7 | |
| SCHEMBL3357611 | 0.81 | CDC7 (0.43) | NPC1ALDH1A1POLBMAPTRAB9A | |
| SCHEMBL3355938 | 0.81 | HTR7 (0.52) | NPC1ALDH1A1POLBMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |