Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3357597 | 0.91 | F2RL3 (0.44) | KMT2AF2RL3IRAK4CNR1CNR2 | |
| SCHEMBL3354060 | 0.84 | CNR2 (0.47) | KMT2ACNR1CNR2ALDH1A1MAPT | |
| SCHEMBL3352886 | 0.80 | MAPT (0.42) | KMT2AF2RL3ASH1LCNR2ALDH1A1 | |
| SCHEMBL9029137 | 0.78 | CNR2 (0.56) | KMT2ACNR1CNR2ALDH1A1MAPT | |
| SCHEMBL3352477 | 0.78 | ALDH1A1 (0.52) | KMT2AF2RL3ASH1LALDH1A1HTT | |
| SCHEMBL3357593 | 0.77 | CNR1 (0.47) | KMT2AF2RL3CNR1CNR2ALDH1A1 | |
| SCHEMBL3352610 | 0.76 | F2RL3 (0.39) | KMT2AF2RL3ASH1LALDH1A1HTT | |
| SCHEMBL3354160 | 0.75 | ALDH1A1 (0.50) | KMT2ACNR1CNR2ALDH1A1GAA | |
| SCHEMBL3356042 | 0.73 | CACNB4 (0.52) | KMT2AALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL3351079 | 0.73 | HTR6 (0.48) | ALDH1A1HTTMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |