Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | VDR | P11473 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346900 | 0.85 | L3MBTL1 (0.42) | HTTTDP1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL3170262 | 0.85 | VDR (0.46) | HTTTDP1L3MBTL1VDRGAA | |
| SCHEMBL3349107 | 0.83 | TLR9 (0.47) | HTTTDP1L3MBTL1VDRGAA | |
| SCHEMBL3347442 | 0.74 | ACHE (0.48) | GAAKMT2AMEN1ALDH1A1CYP3A4 | |
| SCHEMBL3347595 | 0.74 | MMP2 (0.35) | HTTTDP1L3MBTL1GAAKMT2A | |
| SCHEMBL3677020 | 0.72 | ALDH1A1 (0.47) | GAAKMT2AMEN1TLR9ALDH1A1 | |
| SCHEMBL4138555 | 0.71 | HTT (0.61) | HTTTDP1L3MBTL1GAAKMT2A | |
| SCHEMBL5119621 | 0.71 | MAOA (0.46) | HTTL3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL2870280 | 0.71 | BCHE (0.37) | HTTVDRGAAKMT2AMEN1 | |
| SCHEMBL11274295 | 0.70 | L3MBTL1 (0.41) | HTTTDP1L3MBTL1CYP19A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010066357-A1 | BENZOTHIAZOLE AMIDES FOR DETECTION OF AMYLOID BETA | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-06-17 | — | — | WO | disclosed |