Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3354325 | 0.90 | AVPR1A (0.43) | ALDH1A1SMN1; SMN2ACHEPIK3CDPIK3R1 | |
| SCHEMBL3357600 | 0.87 | ACHE (0.42) | ALDH1A1SMN1; SMN2ACHEPIK3CDPIK3R1 | |
| SCHEMBL3357845 | 0.82 | OPRM1 (0.49) | OPRM1OPRD1OPRK1OPRL1AVPR1A | |
| SCHEMBL3357241 | 0.81 | ACHE (0.41) | ALDH1A1ACHEPIK3CDPIK3R1PIK3CA | |
| SCHEMBL3354484 | 0.81 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2ACHEKMT2APOLB | |
| SCHEMBL13537308 | 0.80 | OPRM1 (0.47) | OPRM1OPRD1OPRK1OPRL1AVPR1A | |
| SCHEMBL3355435 | 0.80 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2ACHEKMT2AMEN1 | |
| SCHEMBL3355907 | 0.79 | ACHE (0.39) | ALDH1A1ACHEHIF1A | |
| SCHEMBL3354823 | 0.79 | LMNA (0.43) | ALDH1A1SMN1; SMN2ACHEKMT2AMEN1 | |
| SCHEMBL3352685 | 0.76 | MAPT (0.47) | ALDH1A1ACHELMNAHIF1ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |