Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 3/20 | 0.40 |
| ▸ | EGFR | P00533 | 3/20 | 0.40 |
| ▸ | SRC | P12931 | 3/20 | 0.40 |
| ▸ | ABL2 | P42684 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTR1F | P30939 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 3/20 | 0.37 |
| ▸ | NOS1 | P29475 | 3/20 | 0.37 |
| ▸ | SCD | O00767 | 3/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3357844 | 0.86 | ABL1 (0.44) | DRD2SLC6A4ABL1EGFRSRC | |
| SCHEMBL3354906 | 0.86 | ABL1 (0.44) | DRD2SLC6A4ABL1EGFRSRC | |
| SCHEMBL3352191 | 0.86 | SCD (0.47) | DRD2SLC6A4HTR1AHTR1DHTR1B | |
| SCHEMBL13537514 | 0.84 | NOS3 (0.43) | DRD2SLC6A4ABL1EGFRSRC | |
| SCHEMBL3355827 | 0.82 | HTR7 (0.42) | DRD2SLC6A4HTR1AHTR1DHTR1B | |
| SCHEMBL3355691 | 0.82 | DRD2 (0.52) | DRD2SLC6A4HTR1AHTR1DHTR1B | |
| SCHEMBL3358885 | 0.80 | DRD2 (0.67) | DRD2SLC6A4HTR1AHTR1DHTR1B | |
| SCHEMBL7806905 | 0.78 | DRD2 (0.53) | DRD2SLC6A4 | |
| SCHEMBL3352865 | 0.77 | HTR1D (0.51) | DRD2SLC6A4HTR1AHTR1DHTR1B | |
| SCHEMBL3358927 | 0.77 | DRD2 (0.50) | DRD2SLC6A4HTR1AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |