Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.39 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.39 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | HTR1F | P30939 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3354706 | 0.86 | ALDH1A1 (0.44) | HTR7L3MBTL1ALDH1A1CYP2D6CYP2C9 | |
| SCHEMBL3353063 | 0.86 | HTR7 (0.42) | HTR7L3MBTL1ALDH1A1SMN1; SMN2CYP2D6 | |
| SCHEMBL3354101 | 0.86 | L3MBTL1 (0.48) | HTR7L3MBTL1ALDH1A1CYP2D6CYP2C9 | |
| SCHEMBL3358021 | 0.84 | HTR7 (0.47) | HTR7ALDH1A1SMN1; SMN2DRD2SLC6A4 | |
| SCHEMBL3355552 | 0.82 | DRD2 (0.42) | HTR7DRD2SLC6A4HTR1AHTR1D | |
| SCHEMBL3354104 | 0.82 | DRD2 (0.60) | HTR7ALDH1A1CYP2D6DRD2SLC6A4 | |
| SCHEMBL7805698 | 0.81 | HTR7 (0.45) | HTR7ALDH1A1SMN1; SMN2CYP2C19DRD2 | |
| SCHEMBL7798214 | 0.80 | ACHE (0.59) | DRD2ACHEDRD4 | |
| SCHEMBL3353280 | 0.80 | HTR7 (0.53) | HTR7DRD2SLC6A4CDC7HTR1A | |
| SCHEMBL13537514 | 0.80 | NOS3 (0.43) | HTR7DRD2SLC6A4HTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |