Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | FABP6 | P51161 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL335351 | 0.88 | EGFR (0.50) | RAB9AACP1ABL1FABP6EGFR | |
| SCHEMBL335244 | 0.87 | MAPT (0.41) | RAB9AMAPTACP1ABL1FABP6 | |
| SCHEMBL15282285 | 0.84 | ACP1 (0.46) | RAB9AMAPTACP1ABL1FABP6 | |
| SCHEMBL15282212 | 0.84 | ACP1 (0.46) | RAB9AMAPTACP1ABL1FABP6 | |
| SCHEMBL335570 | 0.83 | PIN1 (0.47) | RAB9AMAPTACP1ABL1FABP6 | |
| SCHEMBL336031 | 0.83 | ABL1 (0.41) | RAB9AMAPTACP1ABL1FABP6 | |
| SCHEMBL335286 | 0.83 | ACP1 (0.42) | RAB9AMAPTACP1ABL1FABP6 | |
| SCHEMBL336047 | 0.83 | POLB (0.43) | ACP1EGFRPIK3CAPOLBKMT2A | |
| SCHEMBL335694 | 0.82 | SMN1; SMN2 (0.39) | RAB9AMAPTACP1ABL1FABP6 | |
| SCHEMBL336367 | 0.82 | MAPT (0.47) | RAB9AMAPTACP1ABL1FABP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097758-B2 | Isoserine derivatives for use as coagulation factor IXa inhibitors | SANOFI-AVENTIS (FR) | 2012-01-17 | — | — | US | claimed |