Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 3/20 | 0.38 |
| ▸ | F9 | P00740 | 2/20 | 0.38 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.37 |
| ▸ | F11 | P03951 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | PYGL | P06737 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL336071 | 0.90 | PYGL (0.45) | MEN1KMT2APYGLACHE | |
| SCHEMBL335308 | 0.90 | MEN1 (0.44) | POLBMEN1KMT2ARXFP1EGFR | |
| SCHEMBL335351 | 0.87 | EGFR (0.50) | ACP1EGFRPIK3CAPYGL | |
| SCHEMBL335551 | 0.85 | KDM4E (0.43) | MEN1KMT2AEGFRPIK3CAPYGL | |
| SCHEMBL335316 | 0.84 | ALOX15 (0.41) | F7F9F3 | |
| SCHEMBL335498 | 0.84 | TAS1R3 (0.45) | F7F9F3F11DYRK1A | |
| SCHEMBL334843 | 0.83 | KDR (0.45) | MEN1KMT2AF7F9F11 | |
| SCHEMBL335582 | 0.83 | TNIK (0.42) | POLBKMT2AACP1EGFRPIK3CA | |
| SCHEMBL15282285 | 0.81 | ACP1 (0.46) | POLBMEN1KMT2AF7ACP1 | |
| SCHEMBL15282212 | 0.81 | ACP1 (0.46) | POLBMEN1KMT2AF7ACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097758-B2 | Isoserine derivatives for use as coagulation factor IXa inhibitors | SANOFI-AVENTIS (FR) | 2012-01-17 | — | — | US | claimed |