SCHEMBL3357129

SCHEMBL3357129

C=CC1CCCN1Cc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C19 P33261 1/20 0.44
ALDH1A1 P00352 1/20 0.44
SPHK2 Q9NRA0 2/20 0.41
SPHK1 Q9NYA1 2/20 0.41
SIGMAR1 Q99720 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3355254 0.95 OPRD1 (0.42) ALDH1A1
SCHEMBL872390 0.85 FAAH (0.46) CYP1A2CYP3A4CYP2D6CYP2C19ALDH1A1
SCHEMBL11969443 0.85 FAAH (0.46) CYP1A2CYP3A4CYP2D6CYP2C19ALDH1A1
SCHEMBL29159388 0.83 FAAH (0.45) CYP1A2CYP3A4CYP2D6CYP2C19ALDH1A1
SCHEMBL1300042 0.80 ALDH1A1 (0.46) ALDH1A1
SCHEMBL11874623 0.79 MAPT (0.44) CYP2C19SIGMAR1
SCHEMBL3569487 0.78 HRH3 (0.52) ALDH1A1
SCHEMBL4842229 0.78 SIGMAR1 (0.52) CYP1A2CYP3A4CYP2D6CYP2C19ALDH1A1
SCHEMBL4836946 0.78 SIGMAR1 (0.52) CYP1A2CYP3A4CYP2D6CYP2C19ALDH1A1
SCHEMBL4292791 0.78 SIGMAR1 (0.52) CYP1A2CYP3A4CYP2D6CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105061703-B Anion exchange block copolymer, manufacture and application thereof 科腾聚合物美国有限责任公司 2019-03-15 CN claimed
CN-107743498-A Initiator for copolymerization of diene monomer and vinyl aromatic monomer 西索斯公司 2018-02-27 CN claimed
EP-2607103-B1 RUBBER COMPOSITION AND TIRE CONTAINING FUNCTIONALIZED POLYBUTADIENE AND FUNCTIONALIZED STYRENE/BUTADIENE ELASTOMERS GOODYEAR TIRE & RUBBER (US) 2016-04-27 EP claimed
US-20130165578-A1 TIRE WITH RUBBER COMPONENT CONTAINING FUNCTIONALIZED POLYBUTADIENE AND FUNCTIONALIZED STYRENE/BUTADIENE ELASTOMERS FRANCIK WILLIAM PAUL (US) 2013-06-27 US claimed
EP-2607103-A2 Rubber composition and tire containing functionalized polybutadiene and functionalized styrene/butadiene elastomers The Goodyear Tire & Rubber Company (US) 2013-06-26 EP claimed
EP-4543936-A1 ALPHA-OMEGA-FUNCTIONALIZED POLYMERS ARLANXEO Deutschland GmbH (DE) 2025-04-30 EP disclosed
EP-4532221-A1 RUBBER COMPOUNDS OF FUNCTIONALIZED CONJUGATED DIENE RUBBERS AND SILICA FILLERS ARLANXEO Deutschland GmbH (DE) 2025-04-09 EP disclosed
CN-119301161-A Alpha-omega-functionalized polymers 阿朗新科德国有限责任公司 2025-01-10 CN disclosed
CN-119136993-A Rubber compound of functionalized conjugated diene rubber and silica filler 阿朗新科德国有限责任公司 2024-12-13 CN disclosed
CN-118164988-A Pyridazinone derivatives and their use in medicine 成都百裕制药股份有限公司 2024-06-11 CN disclosed
CN-118055862-A Silica reinforced rubber compositions and articles made therefrom 迈图高新材料公司 2024-05-17 CN disclosed
WO-2023247719-A1 ALPHA-OMEGA-FUNCTIONALIZED POLYMERS ARLANXEO DEUTSCHLAND GMBH (DE) 2023-12-28 WO disclosed
US-20120214809-A1 Aminoindane Compounds and Use Thereof in Treating Pain Libertas Bio, Inc. 2012-08-23 US disclosed
EP-2184318-A2 Rubber composition and tire Sumitomo Rubber Industries, Ltd. (JP) 2010-05-12 EP disclosed
EP-2182028-A1 Rubber composition and tire Sumitomo Rubber Industries, Ltd. (JP) 2010-05-05 EP disclosed
US-20100105826-A1 RUBBER COMPOSITION AND TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-04-29 US disclosed
US-20100099795-A1 RUBBER COMPOSITION AND TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-04-22 US disclosed
US-20100099810-A1 POLYMER, RUBBER COMPOSITION AND TIRE USING THE SAME SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-04-22 US disclosed
EP-2177562-A2 Polymer, rubber composition and tire using the same Sumitomo Rubber Industries, Ltd. (JP) 2010-04-21 EP disclosed
US-5508336-A LOW MOLECULAR WEIGHT AND HIGH MOLECULAR WEIGHT POLYMER COMPONENTS, EACH SELECTED FROM CONJUGATED DIENE POLYMER AND VINYLAROMATIC-CONJUGATED DIENE COPOLYMER, CARBON BLACK AND/OR WHITE CARBON BRIDGESTONE CORPORATION (JP) 1996-04-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120214809-A1 Aminoindane Compounds and Use Thereof in Treating Pain TRPA1, TRPV1, TRPV2 CYP1A2 1238/4885CYP3A4 3017/4885CYP2D6 1509/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.