Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR1F | P30939 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3354104 | 0.91 | DRD2 (0.60) | HTR7DRD2SLC6A4CYP1A2KMT2A | |
| SCHEMBL3353280 | 0.86 | HTR7 (0.53) | HTR7DRD2SLC6A4MAPTACHE | |
| SCHEMBL3354826 | 0.85 | HTR7 (0.48) | HTR7DRD2SLC6A4KMT2AALDH1A1 | |
| SCHEMBL7805698 | 0.85 | HTR7 (0.45) | HTR7DRD2SLC6A4ALDH1A1MAPT | |
| SCHEMBL7798214 | 0.84 | ACHE (0.59) | DRD2KMT2AMAPTACHEPKM | |
| SCHEMBL3355827 | 0.84 | HTR7 (0.42) | HTR7DRD2SLC6A4ALDH1A1ACHE | |
| SCHEMBL3354706 | 0.83 | ALDH1A1 (0.44) | HTR7DRD2SLC6A4KMT2AALDH1A1 | |
| SCHEMBL3353063 | 0.83 | HTR7 (0.42) | HTR7DRD2SLC6A4KMT2AALDH1A1 | |
| SCHEMBL3354101 | 0.83 | L3MBTL1 (0.48) | HTR7KMT2AALDH1A1PKMLMNA | |
| SCHEMBL3357415 | 0.83 | HTR7 (0.42) | HTR7DRD2SLC6A4CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |