Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 4/20 | 0.44 |
| ▸ | NOS1 | P29475 | 4/20 | 0.44 |
| ▸ | NOS2 | P35228 | 2/20 | 0.44 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | HTR1F | P30939 | 1/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2264529 | 0.88 | NOS3 (0.52) | NOS3NOS1NOS2PRKCIOPRK1 | |
| SCHEMBL3352865 | 0.81 | HTR1D (0.51) | NOS3NOS1NOS2PRKCIOPRK1 | |
| SCHEMBL3354541 | 0.78 | OPRM1 (0.36) | NOS3NOS1NOS2PRKCIOPRK1 | |
| SCHEMBL3358911 | 0.78 | OPRM1 (0.36) | NOS3NOS1NOS2PRKCIOPRK1 | |
| SCHEMBL3354536 | 0.78 | OPRM1 (0.36) | NOS3NOS1NOS2PRKCIOPRK1 | |
| SCHEMBL3352450 | 0.78 | HTR7 (0.45) | NOS3NOS1NOS2 | |
| SCHEMBL3352455 | 0.78 | HTR7 (0.45) | NOS3NOS1NOS2 | |
| SCHEMBL3357163 | 0.77 | OPRM1 (0.43) | NOS3NOS1NOS2PRKCIOPRK1 | |
| SCHEMBL12253683 | 0.76 | NOS3 (0.55) | NOS3NOS1NOS2PRKCIOPRK1 | |
| SCHEMBL3355266 | 0.76 | NOS3 (0.45) | NOS3NOS1NOS2PRKCIDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |