Water

Water

SCHEMBL3358769

O.O.O.[Ge]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL689537 1.00
Water SCHEMBL689940 1.00
Water SCHEMBL6515859 1.00
Water SCHEMBL5597091 1.00
Water SCHEMBL9694222 1.00
Fluoride SCHEMBL4810356 0.82
Water O 15 SCHEMBL25428717 0.71
Water SCHEMBL15484266 0.71
Water SCHEMBL2121635 0.71
Water SCHEMBL4407393 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115873481-B Coating liquid for non-stick cover and preparation method and application thereof 中瀚新材料科技有限公司 2023-07-21 CN claimed
CN-115873481-A Coating liquid for non-stick cover and preparation method and application thereof 中瀚新材料科技有限公司 2023-03-31 CN claimed
CN-112280445-A Heat-seal coating for milk powder packaging and preparation method thereof 中瀚新材料科技有限公司 2021-01-29 CN claimed
CN-112175563-A High-temperature-resistant cooking heat-sealing coating and preparation method thereof 中瀚新材料科技有限公司 2021-01-05 CN claimed
US-4361579-A TREATMENT OF IMMUNE DISEASES WITH ORGANOGERMANIUM POLYMERS YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1982-11-30 US claimed
EP-0025965-A2 Organogermanium compounds, a method for producing them and pharmaceutical compositions comprising them Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1981-04-01 EP claimed
JP-63230695-A None JP disclosed
CN-112447673-B Semiconductor element and method for manufacturing the same 南亚科技股份有限公司 2024-06-14 CN disclosed
CN-112768448-B Semiconductor element and method for manufacturing the same 南亚科技股份有限公司 2024-05-28 CN disclosed
CN-112736066-B Semiconductor element and method for manufacturing the same 南亚科技股份有限公司 2024-05-28 CN disclosed
CN-112864159-B Semiconductor device with oxide interposer and method of fabricating the same 南亚科技股份有限公司 2024-05-24 CN disclosed
CN-114230725-B Modified polyester film based on ultraviolet light hardening and preparation method thereof 江西昊泽光学膜科技有限公司 2023-08-15 CN disclosed
CN-116473956-A Compositions comprising chemokine receptor pathway inhibitors 戴麦里克斯生物科学有限公司 2023-07-25 CN disclosed
EP-0962477-A2 Method of producing polyester and charging apparatus therefor FUJI PHOTO FILM CO., LTD. (JP) 1999-12-08 EP disclosed
US-5851744-A Photographic film FUJI PHOTO FILM CO., LTD. (JP) 1998-12-22 US disclosed
JP-S63230695-A MANUFACTURE OF CARBOXYETHYL GERMANIUM TRIOXIDE UNGU SUU POOKU 1988-09-27 JP disclosed
US-4361579-A TREATMENT OF IMMUNE DISEASES WITH ORGANOGERMANIUM POLYMERS YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1982-11-30 US disclosed
US-4361579-A TREATMENT OF IMMUNE DISEASES WITH ORGANOGERMANIUM POLYMERS YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1982-11-30 US disclosed
EP-0025965-A2 Organogermanium compounds, a method for producing them and pharmaceutical compositions comprising them Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1981-04-01 EP disclosed
EP-0025965-A2 Organogermanium compounds, a method for producing them and pharmaceutical compositions comprising them Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1981-04-01 EP disclosed