Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCE | Q02156 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MYLK | Q15746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | PRKCG | P05129 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.35 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.34 |
| ▸ | RRM1 | P23921 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.33 |
| ▸ | MTOR | P42345 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10244522 | 0.82 | RRM1 (0.42) | PRKCEALDH1A1SLC22A3ADRB3RRM1 | |
| SCHEMBL335431 | 0.80 | NFKB1 (0.57) | NFKB1SLC22A3BLMPMP22TSHR | |
| SCHEMBL336000 | 0.80 | PRKCI (0.51) | MAPTMEN1ALDH1A1KMT2ATDP1 | |
| SCHEMBL334300 | 0.76 | CACNA1B (0.52) | ALDH1A1CYP1A2TSHRHIF1ALMNA | |
| SCHEMBL335144 | 0.75 | ESR1 (0.45) | MAPTMEN1ALDH1A1KMT2ATDP1 | |
| SCHEMBL335330 | 0.73 | OPRK1 (0.50) | MEN1ALDH1A1KMT2ANFKB1BLM | |
| SCHEMBL334407 | 0.73 | OPRK1 (0.50) | MEN1ALDH1A1KMT2ANFKB1BLM | |
| SCHEMBL19680377 | 0.73 | ALDH1A1 (0.56) | PRKCEMAPTMYLKMEN1ALDH1A1 | |
| SCHEMBL18575578 | 0.73 | HTR1A (0.50) | MAPTMEN1ALDH1A1KMT2ACYP1A2 | |
| SCHEMBL11431814 | 0.71 | ESR1 (0.40) | PRKCEMAPTMYLKMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097708-B2 | 10a-Azalide compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-01-17 | — | — | US | disclosed |
| US-20090281292-A1 | 10a-Azalide Compound | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2009-11-12 | — | — | US | disclosed |
| EP-1985620-A1 | 10a-AZALIDE COMPOUND | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2008-10-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281292-A1 | 10a-Azalide Compound | IL17A, AZI2, HDAC9 | PRKCE 3313/4885MAPT 4302/4885MYLK 1694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.