Prednisolone Phosphoric Acid

SCHEMBL3360895

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nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

NR3C1

The experimentally established mechanism targets of Prednisolone Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	NR3C1 known ✓	P04150	10/20	0.81

▸	HIF1A	Q16665	9/20	0.81

▸	HSD17B10	Q99714	8/20	0.81

▸	PGR	P06401	5/20	0.81

▸	CYP3A4	P08684	4/20	0.81

▸	CYP2C19	P33261	3/20	0.81

▸	ABCB11	O95342	2/20	0.81

▸	SERPINA6	P08185	2/20	0.81

▸	NR3C2	P08235	2/20	0.81

▸	TNF	P01375	1/20	0.81

▸	IL6	P05231	1/20	0.81

▸	AR	P10275	1/20	0.81

▸	GLUL	P15104	1/20	0.81

▸	ADAM17	P78536	1/20	0.81

▸	GPBAR1	Q8TDU6	1/20	0.81

▸	LMNA	P02545	2/20	0.70

▸	ALDH1A1	P00352	2/20	0.59

▸	ABCC4	O15439	1/20	0.59

▸	NR1I2	O75469	1/20	0.59

▸	PDE4D	Q08499	1/20	0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Prednisolone Phosphoric Acid SCHEMBL1650407	0.97	PGR (0.77)	NR3C1HIF1AHSD17B10PGRCYP3A4
Prednisolone Phosphoric Acid SCHEMBL1270166	0.97	PGR (0.77)	NR3C1HIF1AHSD17B10PGRCYP3A4
Prednisolone Phosphoric Acid SCHEMBL23563	0.97	PGR (0.77)	NR3C1HIF1AHSD17B10PGRCYP3A4
Prednisolone Phosphoric Acid SCHEMBL23309835	0.94	HIF1A (0.71)	NR3C1HIF1AHSD17B10PGRCYP3A4
Prednisolone SCHEMBL2233875	0.94	NR3C1 (0.90)	NR3C1HIF1AHSD17B10PGRCYP3A4
Prednisolone SCHEMBL23564	0.94	NR3C1 (0.90)	NR3C1HIF1AHSD17B10PGRCYP3A4
Prednisolone SCHEMBL1930093	0.93	NR3C1 (0.88)	NR3C1HIF1AHSD17B10PGRCYP3A4
Prednisolone Phosphoric Acid SCHEMBL15568676	0.92	PGR (0.75)	NR3C1HIF1AHSD17B10PGRCYP3A4
Prednisolone SCHEMBL4751186	0.91	NR3C1 (0.85)	NR3C1HIF1AHSD17B10PGRCYP3A4
SCHEMBL20451346	0.91	PGR (0.81)	NR3C1HIF1AHSD17B10PGRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2236152-A1	Albumin fusion proteins	HUMAN GENOME SCIENCES, INC. (US)	2010-10-06	—	—	EP	disclosed