SCHEMBL3361471

SCHEMBL3361471

COC(=O)C1C(COC(C)(C)C)C1(C)C

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
POLA1 P09884 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3361579 0.81 POLA1 (0.34) POLA1
SCHEMBL3361010 0.80 DGAT1 (0.31)
SCHEMBL1685671 0.79 PRKCA (0.31) POLA1
SCHEMBL1150190 0.76 LMNA (0.34) POLA1ALDH1A1
SCHEMBL3358613 0.76 POLA1 (0.32) POLA1
SCHEMBL6411212 0.76 HTT (0.41) ALDH1A1
SCHEMBL808998 0.75 POLA1 (0.34) POLA1
SCHEMBL809280 0.75 POLA1 (0.31) POLA1
SCHEMBL1149836 0.75 POLA1 (0.35) POLA1
SCHEMBL1150587 0.75 POLA1 (0.35) POLA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103958533-B Optically active bisoxazoline compound, asymmetric catalyst, and method for producing optically active cyclopropane compound using same SUMITOMO CHEMICAL CO.,LTD. (JP) 2016-02-10 CN disclosed
EP-1783111-B1 METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANECARBOXYLATE COMPOUND SUMITOMO CHEMICAL CO (JP) 2015-04-08 EP disclosed
EP-2781522-A1 OPTICALLY ACTIVE BISOXAZOLINE COMPOUND, ASYMMETRIC CATALYST, AND METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANE COMPOUND USING SAID CATALYST Sumitomo Chemical Company, Limited (JP) 2014-09-24 EP disclosed
CN-103958533-A Optically active bis-oxazoline compound, asymmetric catalyst, and method for producing optically active cyclopropane compound using same SUMITOMO CHEMICAL CO 2014-07-30 CN disclosed
CN-1852887-B Process for producing optically active cyclopropane compound and asymmetric copper complex for use in the same SUMITOMO CO LTD 2012-08-15 CN disclosed
US-7709651-B2 asymmetriccomplex of copper(I) trifluoromethanesulfonate and 1,1-bis[2-[(4S)-(tert-butyl)-oxazoline]]cyclopropane is added to 3-methyl-2-butenyl acetate and ethyl diazoacetate using dichloroethane solvent to effect reaction to produce ethyl 3,3-dimethyl-2-(acetoxymethyl)cyclopropanecarboxylate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-05-04 US disclosed
US-7705165-B2 Method for producing optically active cyclopropanecarboxylate compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-04-27 US disclosed
US-7671210-B2 Process for production of optically active cyclopropanecarboxylate compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
EP-1783130-B1 METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANECARBOXYLATE COMPOUND SUMITOMO CHEMICAL CO (JP) 2009-12-30 EP disclosed
US-20090048450-A1 Process for production of optically active cyclopropanecarboxylate compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-02-19 US disclosed
US-20080027235-A1 Method for Producing Optically Active Cyclopropanecarboxylate Compound SUMITOMO CHEMICAL COMPANY, LIMITED 2008-01-31 US disclosed
EP-1783111-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANECARBOXYLATE COMPOUND Sumitomo Chemical Company, Limited (JP) 2007-05-09 EP disclosed
EP-1783130-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANECARBOXYLATE COMPOUND Sumitomo Chemical Company, Limited (JP) 2007-05-09 EP disclosed
US-20070032659-A1 Process for producing optically active cyclopropane compound and asymmetric copper complex for use in the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-02-08 US disclosed
CN-1852887-A Process for producing optically active cyclopropane compound and asymmetric copper complex for use in the same SUMITOMO CHEMICAL CO (JP) 2006-10-25 CN disclosed
EP-1674445-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANE COMPOUND AND ASYMMETRIC COPPER COMPLEX FOR USE IN THE SAME Sumitomo Chemical Company, Limited (JP) 2006-06-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080027235-A1 Method for Producing Optically Active Cyclopropanecarboxylate Compound ACSL6, AOC1, CA6 POLA1 2556/4885ALDH1A1 1222/4885
US-20090048450-A1 Process for production of optically active cyclopropanecarboxylate compound CBR3, C9, CBR1 POLA1 2124/4885ALDH1A1 1594/4885
US-20070032659-A1 Process for producing optically active cyclopropane compound and asymmetric copper complex for use in the same CBR3, AOC3, CBR1 POLA1 1080/4885ALDH1A1 185/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.