SCHEMBL3361729

SCHEMBL3361729

O=P(O)(O)OS(=O)(=O)C(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.32
BLM P54132 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
PGK1 P00558 1/20 0.31
PGK2 P07205 1/20 0.31
CA7 P43166 1/20 0.30
CA13 Q8N1Q1 1/20 0.30
PTPN1 P18031 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28643625 0.97 FDPS (0.30) FDPSBLMTDP1
SCHEMBL29057342 0.80
SCHEMBL27541430 0.80 CA2 (0.32) CA2
SCHEMBL28435210 0.80 CA1 (0.33) CA1CA2CA7CA13
SCHEMBL29279657 0.75
SCHEMBL28858846 0.74 CA1 (0.36) CA1CA2CA7CA13
SCHEMBL27750279 0.73 CA2 (0.44) CA1CA2
SCHEMBL1493042 0.72
Lithium Ion SCHEMBL31557359 0.72
SCHEMBL28668147 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003035669-A1 AMPHIPHILIC CATIONIC LIPIDS DERIVED FROM CHOLESTEROL STERRENBELD BIOTECHNOLOGIE NORTH AMERICA, INC. (US) 2003-05-01 WO claimed
WO-2024114190-A1 ELECTROLYTE COMPOSITION, METHOD FOR SECONDARY ELECTROLYTE FILLING, AND LITHIUM SECONDARY BATTERY 九江天赐高新材料有限公司 2024-06-06 WO disclosed
CN-111303088-B Synthetic method of difurane compound 南京工业大学 2022-10-14 CN disclosed
CN-114958295-A Ultralow-adhesive-force and low-climbing organic silicon pressure-sensitive adhesive as well as preparation method and application thereof 江苏至昕新材料有限公司 2022-08-30 CN disclosed
CN-114854367-A Anti-fingerprint glass organic silicon pressure-sensitive adhesive and preparation method and application thereof 江苏至昕新材料有限公司 2022-08-05 CN disclosed
CN-102532378-A Catalyst composition for preparing 1,2-polybutadiene, and preparation method for 1,2-polybutadiene CHANGCHUN APPLIED CHEMISTRY 2012-07-04 CN disclosed
US-7649015-B2 Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds GILEAD SCIENCES, INC. (US) 2010-01-19 US disclosed
US-20090247488-A1 ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS CANNIZZARO CARINA 2009-10-01 US disclosed
US-20090227543-A1 PHOSPHONATE COMPOUNDS HAVING IMMUNO-MODULATORY ACTIVITY CANNIZZARO CARINA 2009-09-10 US disclosed
US-7470724-B2 Phosphonate compounds having immuno-modulatory activity GILEAD SCIENCES, INC. (US) 2008-12-30 US disclosed
EP-1620110-A2 IMMUNOMODULATOR PHOSPHONATE CONJUGATES GILEAD SCIENCES, INC. (US) 2006-02-01 EP disclosed
US-20050239054-A1 Method and compositions for identifying anti-HIV therapeutic compounds GILEAD SCIENCES. INC. 2005-10-27 US disclosed
US-20050209197-A1 Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds GILEAD SCIENCES, INC. 2005-09-22 US disclosed
CN-1649885-A Cellular Accumulation of Phosphonate Analogs of HIV Protease Inhibitor Compounds and Such Compounds GILEAD SCIENCES INC (US) 2005-08-03 CN disclosed
WO-2005064008-A1 METHOD AND COMPOSITIONS FOR IDENTIFYING ANTI-HIV THERAPEUTIC COMPOUNDS GILEAD SCIENCES, INC. (US) 2005-07-14 WO disclosed
EP-1509537-A2 CELLULAR ACCUMULATION OF PHOSPHONATE ANALOGS OF HIV PROTEASE INHIBITOR COMPOUNDS AND THE COMPOUNDS AS SUCH GILEAD SCIENCES, INC. (US) 2005-03-02 EP disclosed
WO-2004100960-A2 ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS GILEAD SCIENCES, INC. (US) 2004-11-25 WO disclosed
WO-2004096236-A2 IMMUNOMODULATOR PHOSPHONATE CONJUGATES GILEAD SCIENCES, INC. (US) 2004-11-11 WO disclosed
WO-2003090690-A2 CELLULAR ACCUMULATION OF PHOSPHONATE ANALOGS OF HIV PROTEASE INHIBITOR COMPOUNDS AND THE COMPOUNDS AS SUCH GILEAD SCIENCES, INC. (US) 2003-11-06 WO disclosed
US-5344974-A Process for the preparation of N-acyl derivatives of 5-aminolevulinic acid, as well as the hydrochloride of the free acid SUDZUCKER AKTIENGESELLSCHAFT MANNHEIM/OCHENSFURT (DE) 1994-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090227543-A1 PHOSPHONATE COMPOUNDS HAVING IMMUNO-MODULATORY ACTIVITY PHOSPHO1, NFATC1, IFNG FDPS 363/4885BLM 2871/4885TDP1 2777/4885
US-20050209197-A1 Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds PPA1, PPME1, PNP FDPS 504/4885BLM 4243/4885TDP1 554/4885
US-20050239054-A1 Method and compositions for identifying anti-HIV therapeutic compounds CES1, PNP, PGLS FDPS 330/4885BLM 4340/4885TDP1 1526/4885
US-20090247488-A1 ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS PHOSPHO1, TNF, PTGES FDPS 228/4885BLM 3629/4885TDP1 3075/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.