Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC2 | Q92887 | 1/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 5/20 | 0.38 |
| ▸ | QPCT | Q16769 | 5/20 | 0.38 |
| ▸ | ICMT | O60725 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3362115 | 0.86 | PDE4B (0.36) | ABCC2TLR8CNR2KDM4EHSD17B10 | |
| SCHEMBL3469903 | 0.85 | PDE4B (0.39) | KDM4EHSD17B10PDE4BPDE4DHTR6 | |
| SCHEMBL3468921 | 0.83 | ABCC2 (0.37) | ABCC2TLR8CNR2KDM4EHSD17B10 | |
| SCHEMBL3360889 | 0.80 | MGLL (0.33) | TLR8CNR2KDM4EHSD17B10PDE4B | |
| SCHEMBL3477772 | 0.79 | NPC1 (0.39) | KDM4EHSD17B10PDE4BPDE4D | |
| SCHEMBL3474171 | 0.76 | PDE4B (0.34) | ABCC2TLR8CNR2KDM4EHSD17B10 | |
| SCHEMBL3469068 | 0.75 | CRHR1 (0.34) | ABCC2TLR8CNR2KDM4EHSD17B10 | |
| SCHEMBL3359268 | 0.75 | CRHR1 (0.34) | ABCC2TLR8CNR2KDM4EHSD17B10 | |
| SCHEMBL3468899 | 0.75 | CRHR1 (0.34) | ABCC2TLR8CNR2KDM4EHSD17B10 | |
| SCHEMBL3475364 | 0.74 | ADAM17 (0.34) | ABCC2TLR8CNR2PDE4BPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081835-A2 | BIS-RESORCINYL-TRIAZINE DERIVATIVES AS PROTECTING AGENTS AGAINST UV RADIATION | ISDIN, S. A. (ES) | 2010-07-22 | — | — | WO | disclosed |