Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | SHBG | P04278 | 2/20 | 0.70 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.70 |
| ▸ | G6PD | P11413 | 2/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.70 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.70 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.70 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4892804 | 1.00 | GPBAR1 (0.70) | GPBAR1LMNACYP3A4MEN1KMT2A | |
| SCHEMBL11004575 | 1.00 | GPBAR1 (0.70) | GPBAR1LMNACYP3A4MEN1KMT2A | |
| SCHEMBL1799883 | 1.00 | GPBAR1 (0.70) | GPBAR1LMNACYP3A4MEN1KMT2A | |
| SCHEMBL15463390 | 1.00 | GPBAR1 (0.70) | GPBAR1LMNACYP3A4MEN1KMT2A | |
| SCHEMBL20058395 | 1.00 | GPBAR1 (0.70) | GPBAR1LMNACYP3A4MEN1KMT2A | |
| SCHEMBL4890316 | 1.00 | GPBAR1 (0.70) | GPBAR1LMNACYP3A4MEN1KMT2A | |
| SCHEMBL6938662 | 1.00 | GPBAR1 (0.70) | GPBAR1LMNACYP3A4MEN1KMT2A | |
| SCHEMBL1800894 | 1.00 | GPBAR1 (0.70) | GPBAR1LMNACYP3A4MEN1KMT2A | |
| SCHEMBL14525640 | 1.00 | GPBAR1 (0.70) | GPBAR1LMNACYP3A4MEN1KMT2A | |
| SCHEMBL4893508 | 1.00 | GPBAR1 (0.70) | GPBAR1LMNACYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4562182-A1 | BIOMARKERS FOR DIAGNOSIS AND TREATMENT OF ENDOCRINE HYPERTENSION, AND METHODS OF IDENTIFICATION THEREOF | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2025-06-04 | — | — | EP | claimed |
| WO-2023233945-A1 | BILIARY TRACT CANCER TESTING METHOD | 株式会社日立ハイテク | 2023-12-07 | — | — | WO | claimed |
| US-20230085402-A1 | BIOMARKERS | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2023-03-16 | — | — | US | claimed |
| WO-2022251309-A2 | PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | SIOLTA THERAPEUTICS, INC. (US) | 2022-12-01 | — | — | WO | claimed |
| WO-2017189528-A1 | CORROSION INHIBITOR COMPOSITIONS AND METHODS OF USING SAME | Ecolab USA, Inc. (US) | 2017-11-02 | — | — | WO | claimed |
| US-20170306504-A1 | CORROSION INHIBITOR COMPOSITIONS AND METHODS OF USING SAME | CHAMPIONX LLC | 2017-10-26 | — | — | US | claimed |
| US-20150071857-A1 | STEROID HORMONE AND CHOLESTEROL PATHWAYS AS ONE UNIFIED HOMEOSTATIC SYSTEM | LIGAND PHARMACEUTICALS, INC. | 2015-03-12 | — | — | US | claimed |
| EP-2822556-A1 | STEROID HORMONE AND CHOLESTEROL PATHWAYS AS ONE UNIFIED HOMESTATIC SYSTEM | Ligand Pharmaceuticals Inc. (US) | 2015-01-14 | — | — | EP | claimed |
| US-20130234071-A1 | COMPOSITION OF HUMAN SYNTHETIC URINE | DENEAU JOEL DAVID (US) | 2013-09-12 | — | — | US | claimed |
| WO-2013134311-A1 | STEROID HORMONE AND CHOLESTEROL PATHWAYS AS ONE UNIFIED HOMESTATIC SYSTEM | LIGAND PHARMACEUTICALS, INC. (US) | 2013-09-12 | — | — | WO | claimed |
| EP-4740024-A1 | ENDOMETRIOSIS MARKERS AND METHODS OF DIAGNOSING ENDOMETRIOSIS | The University Court Of The University of Edinburgh (GB) | 2026-05-13 | — | — | EP | disclosed |
| US-20250388973-A1 | MULTI-OMICS ASSESSMENT | PROGNOMIQ INC (US) | 2025-12-25 | — | — | US | disclosed |
| EP-4608419-A1 | METHODS OF GENERATING HORMONE-PRODUCING ORGANOIDS AND REVERSING HYPOGONADISM | Jangobio, LLC (US) | 2025-09-03 | — | — | EP | disclosed |
| US-12329726-B2 | Biomarkers for efficacy of prophylactic treatments against stress-induced affective disorders | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2025-06-17 | — | — | US | disclosed |
| EP-4562182-A1 | BIOMARKERS FOR DIAGNOSIS AND TREATMENT OF ENDOCRINE HYPERTENSION, AND METHODS OF IDENTIFICATION THEREOF | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2025-06-04 | — | — | EP | disclosed |
| US-20140017675-A1 | ULTRA-HIGH-SENSITIVE ASSAY OF PROTEIN AND NUCLEIC ACID AND KIT, AND NOVEL ENZYME SUBSTRATE | Nakaishi, Kazunari (JP) | 2014-01-16 | — | — | US | disclosed |
| WO-2013134311-A1 | STEROID HORMONE AND CHOLESTEROL PATHWAYS AS ONE UNIFIED HOMESTATIC SYSTEM | LIGAND PHARMACEUTICALS, INC. (US) | 2013-09-12 | — | — | WO | disclosed |
| US-20100009970-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | COMBINATORX (SINGAPORE) PTE. LTD. (SG) | 2010-01-14 | — | — | US | disclosed |
| US-20080033046-A1 | Treatment of myocardial infarction with 11HSD1 inhibitors | UNIVERSITY OF EDINBURGH (GB) | 2008-02-07 | — | — | US | disclosed |
| US-20060019400-A1 | Method for the determination of glucuronides in physiological samples | UNIVERSITY OF MARYLAND (US) | 2006-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009970-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | HTR1A, HTR3B, HTR3A | GPBAR1 589/4885LMNA 692/4885CYP3A4 403/4885 |
| US-20250388973-A1 | MULTI-OMICS ASSESSMENT | S100A4, APOL1, SAAL1 | GPBAR1 3843/4885LMNA 2789/4885CYP3A4 1840/4885 |
| US-20080033046-A1 | Treatment of myocardial infarction with 11HSD1 inhibitors | HSD11B1, HSD11B2, CYP11B1 | GPBAR1 533/4885LMNA 4376/4885CYP3A4 145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.