Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3364058 | 0.84 | FABP4 (0.58) | KDM4ESMN1; SMN2FABP4LMNAALDH1A1 | |
| SCHEMBL3364464 | 0.83 | PBRM1 (0.55) | CXCL8KDM4ESMN1; SMN2FABP4LMNA | |
| SCHEMBL3363270 | 0.81 | KDM4E (0.53) | CXCL8KDM4EMAPK8NPC1SMN1; SMN2 | |
| SCHEMBL7036185 | 0.80 | ALDH1A1 (0.48) | KDM4ESMN1; SMN2FABP4LMNAALDH1A1 | |
| SCHEMBL4256425 | 0.80 | FABP4 (0.65) | CXCL8KDM4EMAPK8FABP4LMNA | |
| SCHEMBL27488099 | 0.78 | ALDH1A1 (0.54) | KDM4ESMN1; SMN2ALDH1A1KMT2AAKR1C3 | |
| SCHEMBL21758213 | 0.77 | CYP2C19 (0.51) | KDM4ENPC1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL28289321 | 0.75 | KDM4E (0.64) | CXCL8KDM4EMAPK8NPC1SMN1; SMN2 | |
| SCHEMBL4219603 | 0.73 | MEN1 (0.51) | CXCL8KDM4EMAPK8NPC1SMN1; SMN2 | |
| SCHEMBL28325047 | 0.72 | FABP4 (0.47) | FABP4ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144872-A1 | New Methylenebisphenyl Compounds Useful in the Treatment of Inflammation | BIOLIPOX AB | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144872-A1 | New Methylenebisphenyl Compounds Useful in the Treatment of Inflammation | LTC4S, LTB4R2, LTB4R | CXCL8 867/4885KDM4E 2928/4885MAPK8 4056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.