Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | TTR | P02766 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.54 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | AR | P10275 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3364058 | 0.84 | FABP4 (0.58) | MEN1KMT2ALMNAMT-CO2MAPT | |
| SCHEMBL5455144 | 0.83 | ALDH1A1 (0.57) | PBRM1MEN1KMT2ATTRCYP1A2 | |
| SCHEMBL3363276 | 0.83 | CXCL8 (0.49) | PBRM1MEN1KMT2ACYP1A2LMNA | |
| SCHEMBL3364457 | 0.81 | CLCN2 (0.52) | PBRM1MEN1KMT2ATTRCYP1A2 | |
| SCHEMBL7036185 | 0.80 | ALDH1A1 (0.48) | MEN1KMT2ACYP1A2HPGDLMNA | |
| SCHEMBL30575470 | 0.80 | PBRM1 (0.75) | PBRM1MEN1KMT2ATTRCYP1A2 | |
| SCHEMBL4249088 | 0.80 | PBRM1 (0.75) | PBRM1MEN1KMT2ATTRCYP1A2 | |
| SCHEMBL28297347 | 0.78 | PBRM1 (0.73) | PBRM1MEN1KMT2ATTRCYP1A2 | |
| SCHEMBL27488099 | 0.78 | ALDH1A1 (0.54) | KMT2AHPGDAKR1C3ALDH1A1TSHR | |
| SCHEMBL21758213 | 0.77 | CYP2C19 (0.51) | KMT2AHPGDCYP2C19LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144872-A1 | New Methylenebisphenyl Compounds Useful in the Treatment of Inflammation | BIOLIPOX AB | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144872-A1 | New Methylenebisphenyl Compounds Useful in the Treatment of Inflammation | LTC4S, LTB4R2, LTB4R | PBRM1 4203/4885MEN1 1841/4885KMT2A 4008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.