Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.58 |
| ▸ | CTSV | O60911 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.49 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | NGLY1 | Q96IV0 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.47 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28325047 | 0.88 | FABP4 (0.47) | FABP4CTSVCTSLSIRT2MAPT | |
| SCHEMBL7036185 | 0.84 | ALDH1A1 (0.48) | FABP4ALOX15PTGS1AKR1C3AKR1C2 | |
| SCHEMBL3363276 | 0.84 | CXCL8 (0.49) | FABP4PTGS1AKR1C3AKR1C2TAS2R14 | |
| SCHEMBL3364464 | 0.84 | PBRM1 (0.55) | FABP4MAPTAKR1C3PTGS2MEN1 | |
| SCHEMBL8391639 | 0.83 | FABP4 (0.60) | FABP4CTSVCTSLCXCR2MAPT | |
| SCHEMBL28001924 | 0.81 | CTSV (0.49) | FABP4CTSVCTSLSIRT2MAPT | |
| SCHEMBL27488099 | 0.81 | ALDH1A1 (0.54) | ALOX15AKR1C3KMT2AKDM4EALDH1A1 | |
| SCHEMBL22650199 | 0.81 | FABP4 (0.67) | FABP4CTSVCTSLSIRT2MAPT | |
| SCHEMBL21758213 | 0.80 | CYP2C19 (0.51) | MAPTKMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL30525792 | 0.78 | CTSV (0.67) | FABP4CTSVCTSLSIRT2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144872-A1 | New Methylenebisphenyl Compounds Useful in the Treatment of Inflammation | BIOLIPOX AB | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144872-A1 | New Methylenebisphenyl Compounds Useful in the Treatment of Inflammation | LTC4S, LTB4R2, LTB4R | FABP4 3833/4885CTSV 751/4885CTSL 471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.