Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 4/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | BID | P55957 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3364943 | 0.85 | PPARG (0.49) | PPARGPPARA | |
| SCHEMBL3146260 | 0.81 | CCR2 (0.64) | NOD2NOD1CCR2CA12CA9 | |
| SCHEMBL6960149 | 0.81 | CCR2 (0.70) | NOD2NOD1CCR2CA12CA9 | |
| SCHEMBL6955774 | 0.78 | BCL2 (0.50) | NOD2NOD1CCR2ALDH1A1LMNA | |
| SCHEMBL3364801 | 0.75 | PPARG (0.46) | NOD2NOD1PPARGPPARA | |
| SCHEMBL28246138 | 0.74 | HTR6 (0.52) | NOD2NOD1CCR2CA12CA9 | |
| SCHEMBL3363510 | 0.71 | MEN1 (0.56) | ALDH1A1LMNAMCL1PPARGPPARA | |
| SCHEMBL6966440 | 0.71 | CCR2 (0.45) | NOD2NOD1CCR2ALDH1A1LMNA | |
| SCHEMBL18918630 | 0.70 | NOD1 (0.58) | NOD2NOD1CA12CA9CA2 | |
| SCHEMBL1776579 | 0.70 | NOD1 (0.52) | NOD2NOD1CA12CA9CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118060-B1 | 1-BENZENESULFONYL-1H-INDOLE DERIVATIVES AS INHIBITORS OF CCR9 ACTIVITY | NOVARTIS AG (CH) | 2010-10-06 | — | — | EP | claimed |