Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 3/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 3/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | BID | P55957 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | SPR | P35270 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6958067 | 0.82 | CCR2 (0.62) | CCR2HTR6ACLYNOD2NOD1 | |
| SCHEMBL6960149 | 0.80 | CCR2 (0.70) | CCR2HTR6ACLYNOD2NOD1 | |
| SCHEMBL6965626 | 0.78 | NOD2 (0.50) | CCR2HTR6ACLYNOD2NOD1 | |
| SCHEMBL6955774 | 0.77 | BCL2 (0.50) | CCR2HTR6ACLYNOD2NOD1 | |
| SCHEMBL3363385 | 0.71 | NOD2 (0.46) | CCR2NOD2NOD1BCL2BID | |
| SCHEMBL6959902 | 0.68 | PPARG (0.53) | ACLYALDH1A1PPARG | |
| SCHEMBL6964749 | 0.67 | CCR2 (0.52) | CCR2ACLYNOD1PPARG | |
| SCHEMBL4198025 | 0.65 | MCL1 (0.57) | MCL1ALDH1A1MAPTRECQL | |
| SCHEMBL9666902 | 0.64 | CCR2 (0.61) | CCR2NOD2NOD1ALDH1A1LMNA | |
| SCHEMBL9239991 | 0.63 | CCR2 (0.67) | CCR2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001935-B1 | INDOLE DERIVATIVES AS MCP-1 RECEPTOR ANTAGONISTS | ASTRAZENECA AB (SE) | 2003-10-08 | — | — | EP | claimed |