Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.48 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.47 |
| ▸ | FABP4 | P15090 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | CTSV | O60911 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3364457 | 0.81 | CLCN2 (0.52) | TSHRCLCN2FABP4MEN1MAPT | |
| SCHEMBL3363270 | 0.81 | KDM4E (0.53) | TSHRCLCN2PTPN1MEN1KMT2A | |
| SCHEMBL8285642 | 0.81 | CXCR2 (0.60) | TSHRCXCR2CLCN2FABP4MEN1 | |
| SCHEMBL21758214 | 0.80 | PTPN1 (0.50) | TSHRCLCN2PTPN1PTPN2PTPN6 | |
| SCHEMBL28215961 | 0.79 | TSHR (0.49) | TSHRCLCN2PTPN1PTPN2PTPN6 | |
| SCHEMBL23003 | 0.77 | TSHR (0.79) | TSHRPTPN1PTPN2PTPN6KMT2A | |
| SCHEMBL3364068 | 0.77 | POLB (0.60) | CXCR2FABP4MEN1MAPTKMT2A | |
| SCHEMBL28370887 | 0.76 | TSHR (0.76) | TSHRPTPN1PTPN2PTPN6KMT2A | |
| Ammonia Solution, Strong SCHEMBL27527756 | 0.76 | TSHR (0.76) | TSHRPTPN1PTPN2PTPN6KMT2A | |
| SCHEMBL2406195 | 0.75 | MAPT (0.62) | TSHRCXCR2FABP4MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144872-A1 | New Methylenebisphenyl Compounds Useful in the Treatment of Inflammation | BIOLIPOX AB | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144872-A1 | New Methylenebisphenyl Compounds Useful in the Treatment of Inflammation | LTC4S, LTB4R2, LTB4R | TSHR 1657/4885CXCR2 127/4885CLCN2 2374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.