Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLCN2 | P51788 | 5/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.51 |
| ▸ | TTR | P02766 | 4/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.51 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.51 |
| ▸ | MT-CO2 | P00403 | 2/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.51 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.51 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.51 |
| ▸ | ALB | P02768 | 1/20 | 0.51 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.51 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.51 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.51 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.51 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.51 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3363270 | 0.84 | KDM4E (0.53) | CLCN2PTGS2CXCL8ALBMEN1 | |
| SCHEMBL3364052 | 0.81 | TSHR (0.51) | CLCN2MEN1KMT2AMAPTFABP4 | |
| SCHEMBL3364464 | 0.81 | PBRM1 (0.55) | CLCN2PTGS2TTRCXCL8MT-CO2 | |
| SCHEMBL11580885 | 0.79 | FTO (0.55) | CLCN2PTGS2TTRPTGS1CXCL8 | |
| SCHEMBL7642750 | 0.75 | TSHR (0.57) | MEN1KMT2ATSHR | |
| SCHEMBL374641 | 0.75 | FTO (0.71) | CLCN2PTGS2TTRPTGS1MT-CO2 | |
| SCHEMBL21758214 | 0.74 | PTPN1 (0.50) | CLCN2LMNATSHR | |
| SCHEMBL30575470 | 0.74 | PBRM1 (0.75) | CLCN2PTGS2TTRPTGS1CXCL8 | |
| SCHEMBL4249088 | 0.74 | PBRM1 (0.75) | CLCN2PTGS2TTRPTGS1CXCL8 | |
| SCHEMBL28215961 | 0.73 | TSHR (0.49) | CLCN2MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144872-A1 | New Methylenebisphenyl Compounds Useful in the Treatment of Inflammation | BIOLIPOX AB | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144872-A1 | New Methylenebisphenyl Compounds Useful in the Treatment of Inflammation | LTC4S, LTB4R2, LTB4R | CLCN2 2374/4885PTGS2 40/4885TTR 2433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.