Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1608180 | 0.81 | ERN1 (0.41) | CASP6GPR35ALDH1A1MAPTHPGD | |
| SCHEMBL5231955 | 0.78 | MEN1 (0.51) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8187301 | 0.75 | ALDH1A1 (0.37) | ALDH1A1MAPTHPGDMAPK1COMT | |
| SCHEMBL5231561 | 0.72 | SMN1; SMN2 (0.62) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL5202332 | 0.72 | SMN1; SMN2 (0.49) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL5229628 | 0.71 | SLC9A1 (0.53) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL6976938 | 0.71 | HTT (0.37) | ALDH1A1MAPTHPGDKDM4ETDP1 | |
| SCHEMBL3367675 | 0.68 | COMT (0.46) | ALDH1A1MAPTHPGDPOLBSMN1; SMN2 | |
| SCHEMBL5230123 | 0.67 | CHRNA7 (0.38) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL7448258 | 0.67 | SMN1; SMN2 (0.47) | CASP6ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910325-B1 | NEW PHARMACEUTICAL COMPOUNDS | ORION CORP (FI) | 2010-10-06 | — | — | EP | claimed |