Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GALR2 | O43603 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP10 | Q14694 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5888101 | 0.78 | USP10 (0.49) | HTTALDH1A1POLBSMN1; SMN2GALR2 | |
| SCHEMBL6967133 | 0.77 | ALOX5 (0.33) | ALDH1A1KDM4EMAPT | |
| SCHEMBL8187301 | 0.77 | ALDH1A1 (0.37) | HTTALDH1A1LMNAHPGDVCAM1 | |
| SCHEMBL5231955 | 0.71 | MEN1 (0.51) | ALDH1A1POLBSMN1; SMN2LMNANPSR1 | |
| SCHEMBL3364349 | 0.71 | CASP6 (0.40) | ALDH1A1POLBSMN1; SMN2LMNAHPGD | |
| SCHEMBL5229628 | 0.70 | SLC9A1 (0.53) | ALDH1A1POLBSMN1; SMN2LMNANPSR1 | |
| SCHEMBL6978894 | 0.66 | HSD17B10 (0.37) | HTTALDH1A1HPGDKDM4ETDP1 | |
| SCHEMBL7448258 | 0.66 | SMN1; SMN2 (0.47) | HTTALDH1A1POLBSMN1; SMN2MITF | |
| SCHEMBL5231561 | 0.66 | SMN1; SMN2 (0.62) | HTTALDH1A1POLBSMN1; SMN2LMNA | |
| SCHEMBL5202332 | 0.66 | SMN1; SMN2 (0.49) | HTTALDH1A1POLBSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214316-B1 | FIVE MEMBERED-RING COMPOUNDS AND UTILIZATION THEREOF IN LIQUID CRYSTAL MIXTURES | CLARIANT INT LTD (CH) | 2003-05-07 | — | — | EP | disclosed |
| EP-1214316-A1 | FIVE MEMBERED-RING COMPOUNDS AND UTILIZATION THEREOF IN LIQUID CRYSTAL MIXTURES | CLARIANT INTERNATIONAL LTD. (CH) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001016131-A2 | FIVE MEMBERED-RING COMPOUNDS AND UTILIZATION THEREOF IN LIQUID CRYSTAL MIXTURES | CLARIANT INTERNATIONAL LTD (CH) | 2001-03-08 | — | — | WO | disclosed |