Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.46 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1282544 | 0.86 | CA2 (0.52) | TSHRAPOBEC3AHTTAPOBEC3GPOLB | |
| SCHEMBL191996 | 0.84 | ACHE (0.59) | TSHRHTTTUBB1TUBB4ATUBB | |
| Ammonia Solution, Strong SCHEMBL4946565 | 0.81 | ACHE (0.56) | TSHRHTTTUBB1TUBB4ATUBB | |
| Hydrochloric Acid SCHEMBL4381078 | 0.81 | ACHE (0.56) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL21582165 | 0.80 | TSHR (0.49) | TSHRAPOBEC3AHTTAPOBEC3GPOLB | |
| SCHEMBL14300196 | 0.78 | CA2 (0.45) | TSHRAPOBEC3AHTTAPOBEC3GPOLB | |
| SCHEMBL21264353 | 0.77 | MAPT (0.47) | TSHRHTTPOLBMAPTCYP19A1 | |
| SCHEMBL5236856 | 0.77 | TUBB1 (0.58) | TSHRAPOBEC3AHTTAPOBEC3GTUBB1 | |
| SCHEMBL2529901 | 0.77 | ACHE (0.46) | TSHRHTTPOLBL3MBTL1TUBB1 | |
| SCHEMBL5660899 | 0.77 | POLB (0.47) | TSHRAPOBEC3AHTTAPOBEC3GPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110698352-B | Synthetic method of 3-bromo-5-aminocatechol dimethyl ether | 邢台学院 | 2023-01-17 | — | — | CN | claimed |
| CN-110698352-A | Synthetic method of 3-bromo-5-aminocatechol dimethyl ether | 邢台学院 | 2020-01-17 | — | — | CN | claimed |
| CN-103936631-B | A kind of Biphenyl carbamide compound containing oximido and its preparation method and application | XI'AN JIAOTONG UNIVERSITY (CN) | 2015-08-05 | — | — | CN | claimed |
| CN-103288684-B | Biphenyl carbamide compound with antineoplastic activity and preparation method thereof | UNIV XI AN JIAOTONG | 2014-12-10 | — | — | CN | claimed |
| CN-103936631-A | Oximido diphenyl urea compound as well as preparation method and application thereof | UNIV XI AN JIAOTONG | 2014-07-23 | — | — | CN | claimed |
| CN-103288684-A | Biphenyl carbamide compound with antineoplastic activity and preparation method thereof | UNIV XI AN JIAOTONG | 2013-09-11 | — | — | CN | claimed |
| US-20230263155-A1 | 5-(1H-INDOL-3-YL)-OXAZOLE, -OXADIAZOLE AND -FURAN DERIVATIVES AS ENHANCERS OF SPERM MOTILITY | SPERMATECH AS (NO) | 2023-08-24 | — | — | US | disclosed |
| CN-110698352-B | Synthetic method of 3-bromo-5-aminocatechol dimethyl ether | 邢台学院 | 2023-01-17 | — | — | CN | disclosed |
| CN-110698352-B | Synthetic method of 3-bromo-5-aminocatechol dimethyl ether | 邢台学院 | 2023-01-17 | — | — | CN | disclosed |
| CN-110698352-B | Synthetic method of 3-bromo-5-aminocatechol dimethyl ether | 邢台学院 | 2023-01-17 | — | — | CN | disclosed |
| CN-110698352-A | Synthetic method of 3-bromo-5-aminocatechol dimethyl ether | 邢台学院 | 2020-01-17 | — | — | CN | disclosed |
| CN-110698352-A | Synthetic method of 3-bromo-5-aminocatechol dimethyl ether | 邢台学院 | 2020-01-17 | — | — | CN | disclosed |
| CN-110698352-A | Synthetic method of 3-bromo-5-aminocatechol dimethyl ether | 邢台学院 | 2020-01-17 | — | — | CN | disclosed |
| EP-1711617-A1 | METHOD AND COMPOSITIONS FOR IDENTIFYING ANTI-HIV THERAPEUTICS COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2006-10-18 | — | — | EP | disclosed |
| WO-2005064008-A9 | METHOD AND COMPOSITIONS FOR IDENTIFYING ANTI-HIV THERAPEUTIC COMPOUNDS | GILEAD SCIENCES INC (US) | 2006-09-28 | — | — | WO | disclosed |
| US-20050239054-A1 | Method and compositions for identifying anti-HIV therapeutic compounds | GILEAD SCIENCES. INC. | 2005-10-27 | — | — | US | disclosed |
| US-20050209197-A1 | Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds | GILEAD SCIENCES, INC. | 2005-09-22 | — | — | US | disclosed |
| WO-2005064008-A1 | METHOD AND COMPOSITIONS FOR IDENTIFYING ANTI-HIV THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2005-07-14 | — | — | WO | disclosed |
| EP-1509537-A2 | CELLULAR ACCUMULATION OF PHOSPHONATE ANALOGS OF HIV PROTEASE INHIBITOR COMPOUNDS AND THE COMPOUNDS AS SUCH | GILEAD SCIENCES, INC. (US) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003090690-A2 | CELLULAR ACCUMULATION OF PHOSPHONATE ANALOGS OF HIV PROTEASE INHIBITOR COMPOUNDS AND THE COMPOUNDS AS SUCH | GILEAD SCIENCES, INC. (US) | 2003-11-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230263155-A1 | 5-(1H-INDOL-3-YL)-OXAZOLE, -OXADIAZOLE AND -FURAN DERIVATIVES AS ENHANCERS OF SPERM MOTILITY | NR5A1, NR1I3, NR5A2 | TSHR 226/4885APOBEC3A 2113/4885HTT 968/4885 |
| US-20050209197-A1 | Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds | PPA1, PPME1, PNP | TSHR 4770/4885APOBEC3A 1777/4885HTT 3329/4885 |
| US-20050239054-A1 | Method and compositions for identifying anti-HIV therapeutic compounds | CES1, PNP, PGLS | TSHR 4748/4885APOBEC3A 787/4885HTT 3096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.