SCHEMBL28024155

SCHEMBL28024155

NCc1cccc(-c2cc(-c3cccc4c3Cc3ccccc3-4)ccc2O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.50
BACE1 P56817 1/20 0.39
ENPP2 Q13822 1/20 0.36
PRKAB2 O43741 2/20 0.36
PRKAG1 P54619 2/20 0.36
PRKAA2 P54646 2/20 0.36
PRKAA1 Q13131 2/20 0.36
PRKAG3 Q9UGI9 2/20 0.36
PRKAG2 Q9UGJ0 2/20 0.36
PRKAB1 Q9Y478 2/20 0.36
HTR7 P34969 2/20 0.35
TAAR1 Q96RJ0 1/20 0.35
HSD17B1 P14061 1/20 0.35
HSD17B2 P37059 1/20 0.35
HTR2B P41595 1/20 0.34
HDAC1 Q13547 1/20 0.34
KDR P35968 1/20 0.34
KISS1R Q969F8 1/20 0.34
APP P05067 1/20 0.34
NPC1 O15118 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27835839 0.89 PNMT (0.57) PNMTENPP2HTR7TAAR1HTR2B
SCHEMBL3366835 0.85 HSD17B1 (0.47) PNMTBACE1HTR7HSD17B1HSD17B2
SCHEMBL27688049 0.82 PNMT (0.63) PNMTBACE1PRKAB2PRKAG1PRKAA2
SCHEMBL27343315 0.79 PNMT (0.62) PNMTHTR7TAAR1HTR2BNPC1
SCHEMBL28013145 0.78 PNMT (0.45) PNMTHTR7HTR2BKDRAPP
SCHEMBL28628895 0.78 ALOX5 (0.46) PNMTBACE1HTR7HSD17B1HSD17B2
SCHEMBL21295458 0.78 APP (0.58) PNMTHTR7HTR2BAPPNPC1
SCHEMBL29126292 0.78 HTR1A (0.46) PNMTHTR7
SCHEMBL4640228 0.77 ALDH1A1 (0.49) PNMTPRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL27685461 0.77 MEN1 (0.46) PNMTBACE1APPNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104769007-A Polycarbonate resin, process for producing the same, and optical molded article MITSUBISHI GAS CHEMICAL CO 2015-07-08 CN disclosed