Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Stanolone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 5/20 | 0.77 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.77 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.77 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.77 |
| ▸ | PGR | P06401 | 1/20 | 0.77 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.77 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.77 |
| ▸ | AR | P10275 | 1/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.77 |
| ▸ | MGAM | O43451 | 1/20 | 0.77 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.62 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.62 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.55 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.55 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.55 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Stanolone SCHEMBL23037454 | 0.88 | SHBG (0.90) | SHBGGPBAR1CYP19A1NR3C1PGR | |
| Stanolone SCHEMBL3486722 | 0.88 | SHBG (1.00) | SHBGGPBAR1CYP19A1NR3C1PGR | |
| Stanolone SCHEMBL15963544 | 0.88 | SHBG (1.00) | SHBGGPBAR1CYP19A1NR3C1PGR | |
| Stanolone SCHEMBL9340073 | 0.88 | SHBG (1.00) | SHBGGPBAR1CYP19A1NR3C1PGR | |
| Stanolone SCHEMBL24410503 | 0.88 | SHBG (1.00) | SHBGGPBAR1CYP19A1NR3C1PGR | |
| Stanolone SCHEMBL1570704 | 0.88 | SHBG (1.00) | SHBGGPBAR1CYP19A1NR3C1PGR | |
| Stanolone SCHEMBL1502216 | 0.88 | SHBG (1.00) | SHBGGPBAR1CYP19A1NR3C1PGR | |
| Stanolone SCHEMBL24684703 | 0.88 | SHBG (1.00) | SHBGGPBAR1CYP19A1NR3C1PGR | |
| Stanolone SCHEMBL21442439 | 0.88 | SHBG (1.00) | SHBGGPBAR1CYP19A1NR3C1PGR | |
| Stanolone SCHEMBL619535 | 0.88 | SHBG (1.00) | SHBGGPBAR1CYP19A1NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100009970-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | COMBINATORX (SINGAPORE) PTE. LTD. (SG) | 2010-01-14 | — | — | US | disclosed |
| US-20080161324-A1 | Compositions and methods for treatment of viral diseases | EXCRX (SINGAPORE) PTE. LTD. (F.K.A. COMBINATORX (SINGAPORE) PTE LTD.) (SG) | 2008-07-03 | — | — | US | disclosed |
| WO-2008033466-A2 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | COMBINATORX (SINGAPORE) PRE. LTD. (SG) | 2008-03-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009970-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | HTR1A, HTR3B, HTR3A | SHBG 595/4885GPBAR1 589/4885CYP19A1 1933/4885 |
| US-20080161324-A1 | Compositions and methods for treatment of viral diseases | HAVCR2, EIF2AK2, RNASE1 | SHBG 1022/4885GPBAR1 470/4885CYP19A1 1753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.