Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.40 |
| ▸ | SCN4A | P35499 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 5/20 | 0.39 |
| ▸ | PPARA | Q07869 | 5/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 2/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3364893 | 0.89 | SMN1; SMN2 (0.40) | GSTP1SCN4AMGLLPPARGPPARA | |
| SCHEMBL3365869 | 0.88 | CYP3A4 (0.40) | DHODHCYP2C9 | |
| SCHEMBL3364589 | 0.85 | BRD4 (0.44) | SCN9A | |
| SCHEMBL3365574 | 0.81 | BRD4 (0.47) | MCL1 | |
| SCHEMBL3367042 | 0.81 | DHODH (0.41) | DHODHPPARGPPARACYP2C9 | |
| SCHEMBL3364363 | 0.80 | HSP90AA1 (0.41) | GSTP1SCN4AMGLLPPARGPPARA | |
| SCHEMBL14231105 | 0.80 | GSTP1 (0.40) | GSTP1SCN4AMGLLPPARGPPARA | |
| SCHEMBL3364109 | 0.78 | GABRG2 (0.41) | — | |
| SCHEMBL3365166 | 0.77 | GABRG2 (0.42) | DHODHMCL1 | |
| SCHEMBL3363948 | 0.76 | GPR35 (0.40) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656353-B1 | GABANERGIC MODULATORS | HOFFMANN LA ROCHE (CH) | 2010-01-27 | — | — | EP | claimed |