Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.35 |
| ▸ | YAP1 | P46937 | 1/20 | 0.33 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL213868 | 0.74 | GABRA1 (0.41) | ALDH1A1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL11124893 | 0.74 | KMT2A (0.39) | ALDH1A1TDP1LMNAGABRA1GABRG2 | |
| SCHEMBL6836736 | 0.73 | KDM4E (0.44) | ALDH1A1TDP1LMNAGABRA1GABRG2 | |
| Dimethylamine SCHEMBL10491493 | 0.68 | KDM4E (0.40) | ALDH1A1TDP1LMNAGABRA1GABRG2 | |
| Diethylamine SCHEMBL10491539 | 0.67 | CES2 (0.37) | ALDH1A1TDP1GABRA1GABRG2GABRB3 | |
| SCHEMBL4633787 | 0.58 | MAPT (0.44) | ALDH1A1LMNAGABRA1GABRG2GABRB3 | |
| SCHEMBL15648651 | 0.58 | TSHR (0.39) | ALDH1A1TDP1LMNAGABRA1GABRG2 | |
| SCHEMBL7737214 | 0.58 | KMT2A (0.41) | ALDH1A1LMNAGABRA1GABRG2GABRB3 | |
| Biphenyl SCHEMBL151980 | 0.58 | ALDH1A1 (0.69) | ALDH1A1TDP1LMNAGAATSHR | |
| Biphenyl SCHEMBL11511546 | 0.56 | ALDH1A1 (0.64) | ALDH1A1TDP1LMNAGAAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029572-B1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2010-11-03 | — | — | EP | disclosed |